SCHEMBL6794232

SCHEMBL6794232

CCc1nc2c(N)c(F)cc(Cl)c2o1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 2/20 0.35
IDO1 P14902 1/20 0.33
PDE7B Q9NP56 1/20 0.32
GAA P10253 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
TDO2 P48775 1/20 0.31
TLR8 Q9NR97 1/20 0.30
TLR7 Q9NYK1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6788315 0.77 ALDH1A1 (0.36) PDE7B
SCHEMBL6793928 0.76 GABRA1 (0.35) PDE7B
SCHEMBL6794737 0.71 PDE7B (0.41) PDE7BGAA
SCHEMBL6678092 0.68 LMNA (0.33) FBP1
SCHEMBL6659999 0.67 EGFR (0.33)
SCHEMBL8329490 0.65 TLR8 (0.40) GAAL3MBTL1TLR8TLR7
SCHEMBL18325751 0.65 PDE7B (0.41) PDE7BGAA
SCHEMBL24603703 0.64 CA1 (0.35)
SCHEMBL8111641 0.64 FBP1 (0.42) FBP1
SCHEMBL19914430 0.64 MEN1 (0.36) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040029734-A1 Fused-benzene derivatives useful as herbicides ISHIHARA SANGYO KAISHA, LTD. 2004-02-12 US disclosed
US-6573218-B1 Defoliants containing such as uracil and 1,4-benzoxazole or benzthiazole moieties ISHIHARA SANGYO KAISHA, LTD. (JP) 2003-06-03 US disclosed
EP-1111993-A4 FUSED-BENZENE DERIVATIVES USEFUL AS HERBICIDES ISHIHARA SANGYO KAISHA (JP) 2002-12-04 EP disclosed
EP-1111993-A1 FUSED-BENZENE DERIVATIVES USEFUL AS HERBICIDES ISHIHARA SANGYO KAISHA, LTD. (JP) 2001-07-04 EP disclosed
WO-2000013508-A1 FUSED-BENZENE DERIVATIVES USEFUL AS HERBICIDES ISHIHARA SANGYO KAISHA, LTD. (JP) 2000-03-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040029734-A1 Fused-benzene derivatives useful as herbicides DDT, NQO2, DHRS9 FBP1 2487/4885IDO1 2382/4885PDE7B 4125/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.