Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 3/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18311414 | 0.73 | CA12 (0.55) | MAP4K4CSNK1G2CLK4MKNK2MAP4K5 | |
| SCHEMBL25677401 | 0.72 | MAP4K4 (0.52) | MAP4K4CSNK1G2CLK4MKNK2MAP4K5 | |
| SCHEMBL6797785 | 0.70 | TDP2 (0.43) | MAP4K4CSNK1G2CLK4MKNK2MAP4K5 | |
| SCHEMBL23496926 | 0.69 | PIK3CD (0.55) | MAP4K4CSNK1G2CLK4MKNK2MAP4K5 | |
| SCHEMBL30719636 | 0.69 | PIK3CD (0.55) | MAP4K4CSNK1G2CLK4MKNK2MAP4K5 | |
| SCHEMBL14417402 | 0.69 | HSD17B1 (0.58) | MAP4K4CSNK1G2CLK4MKNK2MAP4K5 | |
| SCHEMBL31010862 | 0.68 | PIK3CD (0.51) | MAP4K4CSNK1G2CLK4MKNK2MAP4K5 | |
| SCHEMBL30323720 | 0.67 | BIRC5 (0.77) | MAP4K4CSNK1G2CLK4MKNK2MAP4K5 | |
| SCHEMBL27631118 | 0.67 | BIRC5 (0.77) | MAP4K4CSNK1G2CLK4MKNK2MAP4K5 | |
| SCHEMBL2772360 | 0.67 | PDGFRB (0.77) | MAP4K4CSNK1G2CLK4MKNK2MAP4K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110809-A1 | Metalloproteinase inhibitors | ASTRAZENECA AB (SE) | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110809-A1 | Metalloproteinase inhibitors | MMP9, MMP2, MMP3 | MAP4K4 3801/4885CSNK1G2 2496/4885CLK4 4877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.