Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29633762 | 0.77 | DRD1 (0.58) | MAPTALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL2914928 | 0.77 | DRD1 (0.58) | MAPTALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL9563396 | 0.76 | ALDH1A1 (0.49) | MAPTALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL2141556 | 0.75 | ALDH1A1 (0.52) | MAPTALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL6797983 | 0.75 | STS (0.56) | MAPTALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL2720506 | 0.74 | ALDH1A1 (0.70) | MAPTALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL6536307 | 0.73 | MAPT (0.58) | MAPTALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL10922236 | 0.73 | SRD5A2 (0.49) | MAPTALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL4620527 | 0.73 | SMN1; SMN2 (0.53) | MAPTALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL15395721 | 0.72 | MAPT (0.50) | MAPTALDH1A1HPGDKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556585-A2 | Condensed camptothecin derivatives their production and use as antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-08-25 | — | — | EP | claimed |