Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | ESR1 | P03372 | 2/20 | 0.57 |
| ▸ | MTTP | P55157 | 10/20 | 0.55 |
| ▸ | APOB | P04114 | 9/20 | 0.55 |
| ▸ | CFTR | P13569 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6664034 | 0.88 | NPC1 (0.60) | NPC1RAB9AMAPTESR1MTTP | |
| SCHEMBL6804147 | 0.85 | NPC1 (0.58) | NPC1RAB9AMAPTCFTRLMNA | |
| SCHEMBL6668194 | 0.83 | MAOA (0.60) | NPC1RAB9AMAPTMTTPAPOB | |
| SCHEMBL22803968 | 0.79 | ESR1 (0.62) | NPC1RAB9AMAPTESR1 | |
| SCHEMBL31393757 | 0.78 | CHRNB2 (0.71) | NPC1RAB9AMTTPAPOBALDH1A1 | |
| SCHEMBL31070252 | 0.78 | NPC1 (0.67) | NPC1RAB9AMAPTCFTRLMNA | |
| SCHEMBL6794747 | 0.78 | PTGS1 (0.60) | NPC1RAB9AMAPTMTTPAPOB | |
| SCHEMBL30668348 | 0.77 | ESR1 (0.53) | NPC1RAB9AMAPTESR1 | |
| SCHEMBL17137021 | 0.77 | ESR1 (0.53) | NPC1RAB9AMAPTESR1 | |
| SCHEMBL6809512 | 0.77 | DHPS (0.55) | MTTPAPOBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | NPC1 40/4885RAB9A 4004/4885MAPT 4047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.