Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 4/20 | 0.55 |
| ▸ | PARP1 | P09874 | 2/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | APOB | P04114 | 1/20 | 0.44 |
| ▸ | MTTP | P55157 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31156433 | 0.83 | DHPS (0.76) | DHPSPARP1RXFP1HTTSTING1 | |
| SCHEMBL7083817 | 0.78 | HTT (0.56) | CHRNB2CHRNB4CHRNA3CHRNA4NTRK1 | |
| SCHEMBL396869 | 0.77 | CFTR (0.57) | NTRK1STING1 | |
| SCHEMBL6800635 | 0.77 | NPC1 (0.58) | GAAAPOBMTTP | |
| SCHEMBL7090984 | 0.76 | PIK3CD (0.63) | — | |
| SCHEMBL6670740 | 0.76 | NTRK1 (0.47) | PARP1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL31423388 | 0.76 | TRPV1 (0.58) | DHPSPARP1RXFP1TRPV1 | |
| SCHEMBL9132799 | 0.76 | LMNA (0.59) | DHPSPARP1HTTGAA | |
| SCHEMBL31156438 | 0.74 | CYP1A2 (0.60) | DHPSPARP1RXFP1TRPV1 | |
| SCHEMBL31393757 | 0.74 | CHRNB2 (0.71) | CHRNB2CHRNB4CHRNA3CHRNA4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | DHPS 4389/4885PARP1 2770/4885CHRNB2 676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.