SCHEMBL6800969

SCHEMBL6800969

Cn1c(NC(=O)Cc2ccc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)cc2)nc2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTTP P55157 10/20 0.47
LMNA P02545 2/20 0.47
MAPT P10636 2/20 0.47
KMT2A Q03164 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
NTRK1 P04629 1/20 0.45
NTRK2 Q16620 1/20 0.45
PDE11A Q9HCR9 1/20 0.45
PDE10A Q9Y233 1/20 0.45
APOB P04114 3/20 0.45
KDM4E B2RXH2 2/20 0.44
TSHR P16473 1/20 0.44
HTT P42858 1/20 0.44
HSD17B10 Q99714 1/20 0.44
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
RORC P51449 1/20 0.43
ALDH1A1 P00352 1/20 0.43
POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6909836 0.81 WNT3A (0.58) MTTPMAPTSMN1; SMN2APOB
SCHEMBL6794283 0.80 MTOR (0.58) MTTPLMNAKMT2AAPOBKDM4E
SCHEMBL6793184 0.79 KMT2A (0.58) MTTPLMNAKMT2ASMN1; SMN2APOB
SCHEMBL6797971 0.79 KMT2A (0.55) MTTPKMT2AAPOBKDM4E
SCHEMBL6799294 0.78 KMT2A (0.56) MTTPKMT2ASMN1; SMN2APOBRORC
SCHEMBL6794977 0.78 KDR (0.47) MTTPAPOBALDH1A1
SCHEMBL3729112 0.78 NR1H4 (0.58) MTTPSMN1; SMN2APOBNPC1RAB9A
SCHEMBL6793668 0.77 ADAMTS7 (0.50) MTTPLMNAMAPTSMN1; SMN2APOB
SCHEMBL13351330 0.77 KDM4E (0.59) MTTPLMNAMAPTKMT2ASMN1; SMN2
SCHEMBL6791069 0.77 PTGS1 (0.58) MTTPSMN1; SMN2APOBRORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors APOB, APOL1, SCARB1 MTTP 363/4885LMNA 1239/4885MAPT 4795/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.