SCHEMBL6793668

SCHEMBL6793668

CCn1nccc1NC(=O)Cc1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ADAMTS7 Q9UKP4 2/20 0.50
KDM4E B2RXH2 2/20 0.48
MTTP P55157 11/20 0.45
GAA P10253 2/20 0.45
MAPT P10636 2/20 0.45
ALDH1A1 P00352 1/20 0.45
LMNA P02545 1/20 0.45
APOB P04114 6/20 0.45
SMN1; SMN2 Q16637 1/20 0.44
SMO Q99835 1/20 0.43
FLT1 P17948 1/20 0.43
KDR P35968 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7137999 0.86 ADAMTS7 (0.50) ADAMTS7KDM4EMTTPGAAMAPT
SCHEMBL6799294 0.80 KMT2A (0.56) MTTPALDH1A1APOBSMN1; SMN2SMO
SCHEMBL6797971 0.79 KMT2A (0.55) KDM4EMTTPAPOBSMOKDR
SCHEMBL3726290 0.78 LMNA (0.56) KDM4EMTTPMAPTLMNAAPOB
SCHEMBL6798808 0.78 KDR (0.56) MTTPGAAMAPTALDH1A1APOB
SCHEMBL6795709 0.78 MEN1 (0.59) MTTPMAPTALDH1A1APOBSMN1; SMN2
SCHEMBL3729112 0.78 NR1H4 (0.58) MTTPALDH1A1APOBSMN1; SMN2
SCHEMBL6793184 0.78 KMT2A (0.58) KDM4EMTTPLMNAAPOBSMN1; SMN2
SCHEMBL6792294 0.78 FFAR2 (0.49) MTTPALDH1A1LMNAAPOBSMO
SCHEMBL6800969 0.77 MTTP (0.47) KDM4EMTTPMAPTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors APOB, APOL1, SCARB1 ADAMTS7 3333/4885KDM4E 3114/4885MTTP 363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.