Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.35 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.35 |
| ▸ | ORAI2 | Q96SN7 | 2/20 | 0.35 |
| ▸ | ORAI3 | Q9BRQ5 | 2/20 | 0.35 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1808334 | 0.79 | ORAI1 (0.39) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL28726874 | 0.76 | LMNA (0.42) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL18526870 | 0.76 | LMNA (0.52) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL3792194 | 0.73 | MAOA (0.42) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL18526877 | 0.73 | LMNA (0.40) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL1722636 | 0.72 | PCSK9 (0.45) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL1676742 | 0.70 | PCSK9 (0.34) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL363448 | 0.70 | TRPV6 (0.46) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL1275435 | 0.69 | PCSK9 (0.47) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL1825455 | 0.69 | ENPP2 (0.41) | PCSK9ORAI1ORAI2ORAI3TRPV6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8735582-B2 | Method for producing carboxylic anhydride and arylboronic acid compound | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2014-05-27 | — | — | US | disclosed |
| WO-2004113351-A2 | BIFUNCTIONAL AMINO-BORON LEWIS ACID - LEWIS BASE CATALYST | UNIVERSITY OF DURHAM (GB) | 2004-12-29 | — | — | WO | disclosed |