Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ORAI1 | Q96D31 | 3/20 | 0.39 |
| ▸ | ORAI2 | Q96SN7 | 3/20 | 0.39 |
| ▸ | ORAI3 | Q9BRQ5 | 3/20 | 0.39 |
| ▸ | TRPV6 | Q9H1D0 | 3/20 | 0.39 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | LYPLA1 | O75608 | 1/20 | 0.38 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31135504 | 0.81 | LYPLA1 (0.54) | LYPLA1LYPLA2ALDH1A1TSHRKDM4E | |
| SCHEMBL6801674 | 0.79 | PCSK9 (0.35) | ORAI1ORAI2ORAI3TRPV6PCSK9 | |
| SCHEMBL1722636 | 0.77 | PCSK9 (0.45) | ORAI1ORAI2ORAI3TRPV6PCSK9 | |
| Phenol SCHEMBL4657389 | 0.74 | CA12 (0.42) | CA4CA14LYPLA1LYPLA2ESR1 | |
| SCHEMBL363448 | 0.74 | TRPV6 (0.46) | ORAI1ORAI2ORAI3TRPV6PCSK9 | |
| SCHEMBL1825455 | 0.73 | ENPP2 (0.41) | ORAI1ORAI2ORAI3TRPV6PCSK9 | |
| SCHEMBL1275435 | 0.73 | PCSK9 (0.47) | ORAI1ORAI2ORAI3TRPV6PCSK9 | |
| SCHEMBL4657393 | 0.73 | SLC6A2 (0.36) | CA4ESR1ESR2ALDH1A1TSHR | |
| SCHEMBL1660275 | 0.72 | TRPV6 (0.44) | ORAI1ORAI2ORAI3TRPV6PCSK9 | |
| SCHEMBL27871 | 0.72 | TRPV6 (0.44) | ORAI1ORAI2ORAI3TRPV6PCSK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884074-B2 | Bi-functional co-polymer use for ophthalmic and other topical and local applications | EYEON PARTICLE SCIENCES LLC (US) | 2018-02-06 | — | — | US | claimed |
| EP-3039403-A1 | METHOD FOR DETECTING TRANSPARENT EXOPOLYMER PARTICLES IN A WATER SAMPLE | Kemira Oyj (FI) | 2016-07-06 | — | — | EP | claimed |
| WO-2015028711-A1 | METHOD FOR DETECTING TRANSPARENT EXOPOLYMER PARTICLES IN A WATER SAMPLE | KEMIRA OYJ (FI) | 2015-03-05 | — | — | WO | claimed |
| US-7029688-B2 | Methods and compositions to prevent formation of adhesions in biological tissues | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2006-04-18 | — | — | US | claimed |
| EP-1009451-B1 | COMPOSITIONS AND THEIR USE TO PREVENT FORMATION OF ADHESIONS IN BIOLOGICAL TISSUES | CALIFORNIA INST OF TECHN (US) | 2003-10-29 | — | — | EP | claimed |
| US-20030185787-A1 | Methods and compositions to prevent formation of adhesions in biological tissues | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2003-10-02 | — | — | US | claimed |
| US-6596267-B1 | Such as ethylene glycol-phenylboronic acid copolymer; prosthetics and implant coatings; readily adsorbs onto body tissues in situ providing steric barrier minimizing post-operative adhesion | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2003-07-22 | — | — | US | claimed |
| EP-1009451-A2 | METHODS AND COMPOSITIONS TO PREVENT FORMATION OF ADHESIONS IN BIOLOGICAL TISSUES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2000-06-21 | — | — | EP | claimed |
| WO-1999010022-A2 | METHODS AND COMPOSITIONS TO PREVENT FORMATION OF ADHESIONS IN BIOLOGICAL TISSUES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1999-03-04 | — | — | WO | claimed |
| US-20250241943-A1 | BI-FUNCTIONAL CO-POLYMER USE FOR OPHTHALMIC AND OTHER TOPICAL AND LOCAL APPLICATIONS | CALM WATER THERAPEUTICS LLC | 2025-07-31 | — | — | US | disclosed |
| US-20240117158-A1 | COMPOSITIONS AND METHODS FOR TREATING A DISORDER OR DEFECT IN SOFT TISSUE | UNIV DREXEL (US) | 2024-04-11 | — | — | US | disclosed |
| US-20220348745-A1 | Compositions and Methods for Treating a Disorder or Defect in Soft Tissue | UNIV DREXEL (US) | 2022-11-03 | — | — | US | disclosed |
| US-20220023334-A1 | BI-FUNCTIONAL CO-POLYMER USE FOR OPHTHALMIC AND OTHER TOPICAL AND LOCAL APPLICATIONS | CALM WATER THERAPEUTICS LLC (US) | 2022-01-27 | — | — | US | disclosed |
| US-11135242-B2 | Bi-functional co-polymer use for ophthalmic and other topical and local applications | CALM WATER THERAPEUTICS LLC (US) | 2021-10-05 | — | — | US | disclosed |
| US-20020061288-A1 | Gels and multilayer surface structures from boronic acid containing polymers | EIDGENOSSISCHE TECHNISCHE HOCHSCHULE ZURICH | 2002-05-23 | — | — | US | disclosed |
| US-6350527-B1 | Gels and multilayer surface structures from boronic acid containing polymers | EIDGENOSSISCHE TECHNISCHE HOCHSCHULE ZURICH (CH) | 2002-02-26 | — | — | US | disclosed |
| EP-1107802-A1 | GELS AND MULTILAYER SURFACE STRUCTURES FROM BORONIC ACID CONTAINING POLYMERS | Eidgenössische Technische Hochschule Zürich (CH) | 2001-06-20 | — | — | EP | disclosed |
| EP-1009451-A2 | METHODS AND COMPOSITIONS TO PREVENT FORMATION OF ADHESIONS IN BIOLOGICAL TISSUES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2000-06-21 | — | — | EP | disclosed |
| WO-2000012146-A1 | GELS AND MULTILAYER SURFACE STRUCTURES FROM BORONIC ACID CONTAINING POLYMERS | EIDGENÖSSISCH TECHNISCHE HOCHSCHULE ZURICH (CH) | 2000-03-09 | — | — | WO | disclosed |
| WO-1999010022-A2 | METHODS AND COMPOSITIONS TO PREVENT FORMATION OF ADHESIONS IN BIOLOGICAL TISSUES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1999-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030185787-A1 | Methods and compositions to prevent formation of adhesions in biological tissues | ITGB6, ITGA6, EPCAM | ORAI1 2779/4885ORAI2 3945/4885ORAI3 3395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.