Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 4/20 | 0.44 |
| ▸ | KLK1 | P06870 | 3/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.43 |
| ▸ | F2 | P00734 | 4/20 | 0.43 |
| ▸ | PLG | P00747 | 3/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.43 |
| ▸ | C1S | P09871 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | TMPRSS15 | P98073 | 4/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL392941 | 0.85 | DGAT1 (0.48) | DGAT1EPHX2NR1H4 | |
| SCHEMBL6808471 | 0.84 | ALDH1A1 (0.46) | PLAUKLK1KLK5PRSS1F2 | |
| Hydrochloric Acid SCHEMBL7034435 | 0.82 | ALDH1A1 (0.44) | PLAUKLK1KLK5PRSS1F2 | |
| SCHEMBL460421 | 0.82 | LMNA (0.55) | EPHX2NR1H4 | |
| SCHEMBL19450839 | 0.81 | DGAT1 (0.42) | DGAT1EPHX2NR1H4 | |
| Hydrochloric Acid SCHEMBL26689957 | 0.80 | LMNA (0.53) | EPHX2NR1H4 | |
| Hydrochloric Acid SCHEMBL4957114 | 0.80 | LMNA (0.53) | EPHX2NR1H4 | |
| SCHEMBL25458525 | 0.79 | ALDH1A1 (0.49) | PLAUKLK1PRSS1F2PLG | |
| Iodide SCHEMBL10426220 | 0.79 | CDC25A (0.47) | PLAUKLK1PRSS1F2PLG | |
| SCHEMBL19014876 | 0.79 | KDM1A (0.42) | DGAT1EPHX2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040014994-A1 | Method for resolving chiral (2s) and (2r) chromanes | ELI LILLY AND COMPANY | 2004-01-22 | — | — | US | disclosed |
| EP-1292588-A1 | METHODS FOR RESOLVING CHIRAL (2S) AND (2R) CHROMANES | Eli Lilly & Company (US) | 2003-03-19 | — | — | EP | disclosed |
| EP-1286982-A2 | PROCESS FOR THE PREPARATION OF BENZOYL SUBSTITUTED BICYLIC COMPOUNDS AND CHIRAL BNEZOPYRAN DERIVATIVES | Eli Lilly & Company (US) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001094333-A2 | PROCESS FOR THE PREPARATION OF BENZOYL SUBSTITUTED BICYCLIC COMPOUNDS AND CHIRAL BENZOPYRAN DERIVATIVES | ELI LILLY & COMPANY (US) | 2001-12-13 | — | — | WO | disclosed |
| WO-2001094334-A1 | METHODS FOR RESOLVING CHIRAL (2S) AND (2R) CHROMANES | ELI LILLY & COMPANY (US) | 2001-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014994-A1 | Method for resolving chiral (2s) and (2r) chromanes | TBXA2R, TBXAS1, SRR | PLAU 425/4885KLK1 3381/4885KLK5 4212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.