Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 5/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6808948 | 0.74 | ALDH1A1 (0.43) | ESR1ESR2SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL22978798 | 0.72 | KCNA3 (0.44) | KCNA3SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL6807682 | 0.72 | SLC6A4 (0.41) | SLC6A4SLC6A3SLC6A2L3MBTL1ALDH1A1 | |
| SCHEMBL6802473 | 0.70 | OPRM1 (0.47) | ADRB2HTTALDH1A1 | |
| SCHEMBL6803510 | 0.70 | ALDH1A1 (0.37) | ESR1ESR2HDAC8HDAC6SLC6A4 | |
| SCHEMBL22996026 | 0.70 | KCNA3 (0.45) | KCNA3SLC6A4SLC6A2 | |
| SCHEMBL5314616 | 0.69 | ESR1 (0.69) | KCNA3ESR1ESR2LMNAL3MBTL1 | |
| SCHEMBL16291586 | 0.69 | SLC6A2 (0.54) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL11230906 | 0.68 | ADRB2 (0.44) | ESR1ESR2HDAC6ADRB2CA1 | |
| SCHEMBL6804377 | 0.68 | LTA4H (0.33) | ADRB2LMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063643-A1 | Bombesin antagonists | PFIZER INC. | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063643-A1 | Bombesin antagonists | BRS3, NPSR1, GNRHR | KCNA3 531/4885ESR1 178/4885ESR2 375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.