Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.38 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6223385 | 0.73 | SLC6A3 (0.60) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL6808948 | 0.72 | ALDH1A1 (0.43) | SLC6A4SLC6A3SLC6A2KDM4EALDH1A1 | |
| SCHEMBL6802801 | 0.72 | KCNA3 (0.43) | SLC6A4SLC6A3SLC6A2ALDH1A1TSHR | |
| SCHEMBL6803510 | 0.71 | ALDH1A1 (0.37) | SLC6A4ALDH1A1 | |
| SCHEMBL6803816 | 0.70 | SOAT1 (0.49) | KDM4ESOAT2ACAT1SOAT1BACE1 | |
| SCHEMBL6802473 | 0.68 | OPRM1 (0.47) | KDM4EALDH1A1OPRM1 | |
| SCHEMBL5736003 | 0.68 | KDM4E (0.45) | SLC6A4SLC6A3SLC6A2KDM4EBACE1 | |
| SCHEMBL6202623 | 0.68 | ADRB2 (0.38) | SLC6A4SLC6A3SLC6A2ALDH1A1TSHR | |
| SCHEMBL6804377 | 0.66 | LTA4H (0.33) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29234167 | 0.66 | APP (0.50) | KDM4EALDH1A1TSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063643-A1 | Bombesin antagonists | PFIZER INC. | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063643-A1 | Bombesin antagonists | BRS3, NPSR1, GNRHR | SLC6A4 419/4885SLC6A3 465/4885SLC6A2 256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.