Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 15/20 | 0.39 |
| ▸ | MMP12 | P39900 | 5/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 9/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL940675 | 0.93 | MMP13 (0.44) | MMP13MMP12MMP1MMP14ADAM17 | |
| Trifluoroacetic Acid SCHEMBL942607 | 0.91 | MMP13 (0.44) | MMP13MMP12MMP1MMP14KCNH2 | |
| Trifluoroacetic Acid SCHEMBL6916856 | 0.90 | MMP13 (0.41) | MMP13MMP12MMP1MMP14KCNH2 | |
| SCHEMBL7013882 | 0.82 | MMP1 (0.46) | MMP13MMP12MMP1MMP14KCNH2 | |
| Trifluoroacetic Acid SCHEMBL943119 | 0.81 | MMP13 (0.41) | MMP13MMP12MMP1MMP14KCNH2 | |
| SCHEMBL940710 | 0.80 | MMP13 (0.49) | MMP13MMP12MMP1MMP14FPR2 | |
| Trifluoroacetic Acid SCHEMBL941448 | 0.78 | MMP13 (0.46) | MMP13MMP12MMP1MMP14KCNH2 | |
| SCHEMBL943704 | 0.77 | MMP13 (0.54) | MMP13MMP12MMP1MMP14FPR2 | |
| SCHEMBL7013880 | 0.77 | MMP1 (0.47) | MMP13MMP12MMP1MMP14KCNH2 | |
| SCHEMBL941602 | 0.76 | MMP13 (0.49) | MMP13MMP12MMP1MMP14ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040127528-A1 | Metalloproteinase inhibitors | ASTRAZENECA AB (SE) | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127528-A1 | Metalloproteinase inhibitors | MMP9, MMP10, MMP3 | MMP13 10/4885MMP12 5/4885MMP1 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.