Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | TPMT | P51580 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16510468 | 0.91 | MAPT (0.47) | MAPTSMN1; SMN2TSHRKMT2AALDH1A1 | |
| SCHEMBL6797429 | 0.89 | TUBB1 (0.46) | MAPTSMN1; SMN2KMT2AALDH1A1MEN1 | |
| SCHEMBL19866164 | 0.89 | MAPT (0.46) | MAPTSMN1; SMN2TSHRCYP1A2CYP3A4 | |
| SCHEMBL6613832 | 0.88 | RAB9A (0.52) | MAPTSMN1; SMN2KMT2AALDH1A1MEN1 | |
| SCHEMBL14702313 | 0.85 | MAPT (0.46) | MAPTTSHRCYP3A4KMT2AALDH1A1 | |
| SCHEMBL6803101 | 0.85 | MAPT (0.54) | MAPTSMN1; SMN2TSHRCYP1A2CYP3A4 | |
| SCHEMBL6803587 | 0.84 | KMT2A (0.45) | MAPTSMN1; SMN2KMT2AALDH1A1MEN1 | |
| SCHEMBL16704749 | 0.84 | KMT2A (0.53) | MAPTSMN1; SMN2TSHRCYP3A4KMT2A | |
| SCHEMBL6612207 | 0.83 | ALDH1A1 (0.60) | SMN1; SMN2CYP1A2KMT2AALDH1A1MEN1 | |
| SCHEMBL1849992 | 0.82 | MAPT (0.49) | MAPTSMN1; SMN2TSHRCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040087582-A1 | Phenyl derivatives | MERCK PATENT GESELLSCHAFT (DE) | 2004-05-06 | — | — | US | claimed |
| US-6710063-B1 | Activators of PPAR delta | SMITHKLINE BEECHAM CORPORATION | 2004-03-23 | — | — | US | claimed |
| US-10426757-B2 | Compositions and methods for promoting intestinal stem cell and/or non-stem progenitor cell function | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2019-10-01 | — | — | US | disclosed |
| US-20040063665-A1 | Substituted benzopyranones as telomerase inhibitors | PHARMACIA ITALIA S.P.A. (IT) | 2004-04-01 | — | — | US | disclosed |
| US-20020160983-A1 | Substituted benzopyranones as telomerase inhibitors | PHARMACIA ITALIA S.P.A. (IT) | 2002-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10426757-B2 | Compositions and methods for promoting intestinal stem cell and/or non-stem progenitor cell function | FABP2, ALPG, ALPI | MAPT 4869/4885SMN1; SMN2 3086/4885TSHR 4242/4885 |
| US-20020160983-A1 | Substituted benzopyranones as telomerase inhibitors | TERT, TERF2, TERF2IP | MAPT 1629/4885SMN1; SMN2 1470/4885TSHR 3660/4885 |
| US-20040087582-A1 | Phenyl derivatives | F2, F11, SERPINC1 | MAPT 4360/4885SMN1; SMN2 3430/4885TSHR 1763/4885 |
| US-20040063665-A1 | Substituted benzopyranones as telomerase inhibitors | TERT, TERF2, TERF2IP | MAPT 1628/4885SMN1; SMN2 1466/4885TSHR 3682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.