Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | SOD1 | P00441 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6804907 | 0.84 | MAOB (0.41) | MAOBAPPNR4A2MAOA | |
| SCHEMBL6809550 | 0.83 | MMP2 (0.46) | MAOBAPPRXRARXRBMAOA | |
| SCHEMBL6804913 | 0.80 | PARP10 (0.56) | MAOBMAOA | |
| SCHEMBL6804638 | 0.78 | GRM5 (0.41) | MAOBMAOA | |
| SCHEMBL6803571 | 0.78 | RAB9A (0.40) | MAOBAPPMAOASOD1 | |
| SCHEMBL6805048 | 0.77 | LMNA (0.58) | MAOBAPPNR4A2MAOA | |
| SCHEMBL7782082 | 0.77 | LMNA (0.57) | MAOBAPPNR4A2RXRARXRB | |
| SCHEMBL6804893 | 0.76 | SOD1 (0.42) | MAOBAPPRXRARXRBMAOA | |
| SCHEMBL6810689 | 0.76 | MAPT (0.39) | MAOBAPP | |
| SCHEMBL6804822 | 0.75 | SMN1; SMN2 (0.54) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6770647-B2 | Bicyclic hydroxamates as inhibitors of matrix metalloproteinases and/or TNF-α converting enzyme (TACE) | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2004-08-03 | — | — | US | disclosed |