Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.40 |
| ▸ | ITGAV | P06756 | 11/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4640097 | 0.92 | TDP1 (0.36) | ITGB3ITGAVTDP1KMT2APOLB | |
| SCHEMBL6811091 | 0.85 | ITGB3 (0.53) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL4640085 | 0.84 | ITGAV (0.38) | ITGB3ITGAVMAPTITGA2BITGB5 | |
| SCHEMBL6805973 | 0.82 | TDP1 (0.43) | TDP1KMT2APOLBMAPTKDM4E | |
| SCHEMBL27524220 | 0.81 | ITGB3 (0.46) | ITGB3ITGAVITGA2BITGB5HRH4 | |
| SCHEMBL4640164 | 0.81 | ITGB3 (0.46) | ITGB3ITGAVITGA2BITGB5HRH4 | |
| SCHEMBL6810270 | 0.79 | NPEPPS (0.34) | ITGB3ITGAVTDP1KMT2APOLB | |
| SCHEMBL27474218 | 0.79 | KMT2A (0.39) | TDP1KMT2APOLBMAPTKDM4E | |
| SCHEMBL4640715 | 0.79 | KMT2A (0.39) | TDP1KMT2APOLBMAPTKDM4E | |
| SCHEMBL4641013 | 0.77 | ITGB3 (0.34) | ITGB3ITGAVKMT2AMAPTITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723727-B1 | VITRONECTIN RECEPTOR ANTAGONISTS; INHIBITORS OF BONE RESORPTION; OSTEOPOROSIS | HOECHST AKTIENGESELLSCHAFT (DE) | 2004-04-20 | — | — | US | disclosed |