Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.40 |
| ▸ | ITGAV | P06756 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4640795 | 0.91 | SLC29A1 (0.38) | ITGB3ITGAVALDH1A1DOT1LCYP1A2 | |
| SCHEMBL4641344 | 0.86 | ITGB3 (0.48) | ITGB3ITGAV | |
| SCHEMBL6807083 | 0.82 | CASP1 (0.37) | DOT1L | |
| SCHEMBL5840142 | 0.79 | HDAC6 (0.47) | ITGB3ITGAVPPARGPPARA | |
| SCHEMBL6807305 | 0.78 | SYK (0.36) | DOT1L | |
| SCHEMBL4641533 | 0.78 | ITGB3 (0.42) | ITGB3ITGAV | |
| SCHEMBL4640796 | 0.77 | ITGB3 (0.47) | ITGB3ITGAV | |
| SCHEMBL4640793 | 0.77 | ITGB3 (0.47) | ITGB3ITGAV | |
| SCHEMBL4641283 | 0.75 | ITGB3 (0.46) | ITGB3ITGAV | |
| SCHEMBL4641583 | 0.74 | ITGB3 (0.55) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723727-B1 | VITRONECTIN RECEPTOR ANTAGONISTS; INHIBITORS OF BONE RESORPTION; OSTEOPOROSIS | HOECHST AKTIENGESELLSCHAFT (DE) | 2004-04-20 | — | — | US | disclosed |