Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 5/20 | 0.42 |
| ▸ | CASP7 | P55210 | 5/20 | 0.42 |
| ▸ | CASP6 | P55212 | 5/20 | 0.42 |
| ▸ | CASP8 | Q14790 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6809085 | 0.99 | CASP3 (0.43) | CASP3ALDH1A1CASP1CASP7CASP6 | |
| SCHEMBL6808837 | 0.88 | CTSS (0.46) | CASP3ALDH1A1CASP1MAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL6805507 | 0.87 | CTSS (0.45) | CASP3ALDH1A1CASP1MAPK1L3MBTL1 | |
| SCHEMBL6812947 | 0.84 | CTSL (0.43) | ALDH1A1L3MBTL1POLB | |
| Hydrochloric Acid SCHEMBL6813149 | 0.83 | CTSL (0.43) | ALDH1A1L3MBTL1POLB | |
| SCHEMBL6809092 | 0.80 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1TP53 | |
| Hydrochloric Acid SCHEMBL6808628 | 0.79 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1SMN1; SMN2TP53 | |
| SCHEMBL6807390 | 0.78 | TSHR (0.37) | ALDH1A1MAPK1L3MBTL1SMN1; SMN2TP53 | |
| SCHEMBL6808494 | 0.78 | CTSL (0.43) | ALDH1A1MAPK1L3MBTL1TP53 | |
| Hydrochloric Acid SCHEMBL6812867 | 0.77 | TSHR (0.36) | ALDH1A1MAPK1L3MBTL1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040204368-A1 | Oxadiazole derivative compounds and drugs containing these compounds as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-10-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040204368-A1 | Oxadiazole derivative compounds and drugs containing these compounds as the active ingredient | ACIN1, CASP3, CASP7 | CASP3 2/4885ALDH1A1 1531/4885CASP1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.