SCHEMBL6807255

SCHEMBL6807255

CC(=O)Nc1cc(N)c(NS(=O)(=O)c2ccccc2)c(O)c1

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.51
GFER P55789 3/20 0.51
GAA P10253 3/20 0.51
MEN1 O00255 2/20 0.51
MAPT P10636 3/20 0.47
POLB P06746 2/20 0.47
CYTH2 Q99418 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
APAF1 O14727 1/20 0.47
CASP6 P55212 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
IDO1 P14902 1/20 0.46
HTT P42858 1/20 0.46
ALDH1A1 P00352 2/20 0.45
BDKRB1 P46663 1/20 0.45
KDM4E B2RXH2 2/20 0.45
PKM P14618 1/20 0.45
APOBEC3G Q9HC16 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6800198 0.82 LMNA (0.43) GAATDP1ALDH1A1PKM
SCHEMBL6807722 0.80 CYTH2 (0.54) KMT2AGFERGAAMEN1POLB
SCHEMBL6805921 0.78 KMT2A (0.62) KMT2AGFERGAAMEN1MAPT
SCHEMBL8921186 0.76 PKM (0.64) KMT2AGFERGAAMEN1HTT
SCHEMBL11700730 0.75 MEN1 (0.82) KMT2AGFERGAAMEN1MAPT
SCHEMBL8920534 0.74 PKM (0.67) KMT2AGFERGAAMEN1MAPT
SCHEMBL6807829 0.74 G6PD (0.56) KMT2AGFERGAAMEN1MAPT
SCHEMBL8016507 0.73 GAA (0.69) KMT2AGFERGAAMEN1POLB
SCHEMBL6807397 0.72 KMT2A (0.61) KMT2AGFERGAAMEN1MAPT
SCHEMBL11774185 0.71 ALDH1A1 (0.59) KMT2AGAAMEN1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6733540-B2 FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES L'OREAL (FR) 2004-05-11 US claimed
US-20020100125-A1 Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring L'OREAL (FR) 2002-08-01 US claimed
EP-1205176-A1 Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing L'OREAL (FR) 2002-05-15 EP claimed
US-6733540-B2 FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES L'OREAL (FR) 2004-05-11 US disclosed
US-20020100125-A1 Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring L'OREAL (FR) 2002-08-01 US disclosed
EP-1205176-A1 Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing L'OREAL (FR) 2002-05-15 EP disclosed