Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685966 | 0.68 | ALDH1A1 (0.37) | ALDH1A1LMNAMAPTCYP19A1TSHR | |
| SCHEMBL11301702 | 0.68 | ALDH1A1 (0.37) | ALDH1A1LMNAMAPTCYP19A1TSHR | |
| SCHEMBL7057172 | 0.64 | ALDH1A1 (0.33) | ALDH1A1LMNAMAPTCYP19A1TSHR | |
| SCHEMBL8108558 | 0.64 | HSP90AA1 (0.35) | ALDH1A1LMNAMAPTCYP19A1TSHR | |
| SCHEMBL22471432 | 0.64 | PGR (0.36) | ALDH1A1LMNAMAPTCYP19A1TSHR | |
| SCHEMBL4428227 | 0.64 | ALDH1A1 (0.33) | ALDH1A1LMNAMAPTCYP19A1TSHR | |
| SCHEMBL17356348 | 0.64 | LMNA (0.36) | ALDH1A1LMNAMAPTCYP19A1TSHR | |
| SCHEMBL11414767 | 0.64 | ALDH1A1 (0.33) | ALDH1A1LMNAMAPTCYP19A1TSHR | |
| SCHEMBL22846898 | 0.63 | ALDH1A1 (0.32) | ALDH1A1LMNAMAPTCYP19A1TSHR | |
| SCHEMBL22847505 | 0.62 | ADRA1D (0.37) | ALDH1A1LMNAMAPTCYP19A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12359222-B2 | DNA plasmids for the fast generation of homologous recombination vectors for cell line development | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2025-07-15 | — | — | US | disclosed |
| WO-2025106834-A1 | A SINGLE-PLASMID SYSTEM FOR ENHANCED CRISPR-CAS9 MEDIATED HOMOLOGOUS RECOMBINATION | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2025-05-22 | — | — | WO | disclosed |
| US-20240374761-A1 | ANIMAL MODEL HAVING HOMOLOGOUS RECOMBINATION OF MOUSE PTH1 RECEPTOR | RADIUS PHARMACEUTICALS INC (US) | 2024-11-14 | — | — | US | disclosed |
| CN-110199020-B | DNA plasmid for rapid generation of homologous recombination vectors for cell line development | 坦普尔大学-高等教育联盟 | 2024-06-18 | — | — | CN | disclosed |
| WO-2024086848-A2 | A CRISPR COUNTER-SELECTION INTERRUPTION CIRCUIT (CCIC) AND METHODS OF USE THEREOF | THE ROCKEFELLER UNIVERSITY (US) | 2024-04-25 | — | — | WO | disclosed |
| US-20230357754-A1 | RAPID EXTRACELLULAR ANTIBODY PROFILING (REAP) FOR THE DISCOVERY AND USE OF SAID ANTIBODIES | YALE UNIVERSITY | 2023-11-09 | — | — | US | disclosed |
| EP-4219709-A1 | DNA PLASMIDS FOR THE FAST GENERATION OF HOMOLOGOUS RECOMBINATION VECTORS FOR CELL LINE DEVELOPMENT | Temple University - Of The Commonwealth System of Higher Education (US) | 2023-08-02 | — | — | EP | disclosed |
| EP-3535394-B1 | DNA PLASMIDS FOR THE FAST GENERATION OF HOMOLOGOUS RECOMBINATION VECTORS FOR CELL LINE DEVELOPMENT | UNIV TEMPLE (US) | 2023-04-12 | — | — | EP | disclosed |
| EP-4121583-A1 | RAPID EXTRACELLULAR ANTIBODY PROFILING (REAP) FOR THE DISCOVERY AND USE OF SAID ANTIBODIES | Yale University (US) | 2023-01-25 | — | — | EP | disclosed |
| WO-2022235929-A1 | ANIMAL MODEL HAVING HOMOLOGOUS RECOMBINATION OF MOUSE PTH1 RECEPTOR | RADIUS PHARMACEUTICALS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |
| US-20200109434-A1 | Compositions and Methods for Diagnosing Recurrent Focal and Segmental Glomerulosclerosis (rFSGS) | MEDICAL UNIVERSITY OF SOUTH CAROLINA | 2020-04-09 | — | — | US | disclosed |
| US-20190284582-A1 | DNA Plasmids for the Fast Generation of Homologous Recombination Vectors for Cell Line Development | Temple University—Of the Commonwealth System of Higher Education | 2019-09-19 | — | — | US | disclosed |
| EP-3535394-A2 | DNA PLASMIDS FOR THE FAST GENERATION OF HOMOLOGOUS RECOMBINATION VECTORS FOR CELL LINE DEVELOPMENT | Temple University - Of The Commonwealth System of Higher Education (US) | 2019-09-11 | — | — | EP | disclosed |
| WO-2018144087-A2 | DNA PLASMIDS FOR THE FAST GENERATION OF HOMOLOGOUS RECOMBINATION VECTORS FOR CELL LINE DEVELOPMENT | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2018-08-09 | — | — | WO | disclosed |
| US-20040137490-A1 | Methods for making polynucleotide libraries, polynucleotide arrays, and cell libraries for high-throughput genomics analysis | PANGENEX, INC. | 2004-07-15 | — | — | US | disclosed |
| US-20030143597-A1 | Methods for making polynucleotide libraries, polynucleotide arrays, and cell libraries for high-throughput genomics analysis | PANGENEX, INC. | 2003-07-31 | — | — | US | disclosed |
| US-20020150945-A1 | Methods for making polynucleotide libraries, polynucleotide arrays, and cell libraries for high-throughput genomics analysis | CELL THERAPEUTICS, INC. | 2002-10-17 | — | — | US | disclosed |
| US-20020123065-A1 | Methods for making polynucleotide libraries, polynucleotide arrays, and cell libraries for high-throughput genomics analysis | PANGENEX, INC. | 2002-09-05 | — | — | US | disclosed |
| US-20020094536-A1 | Methods for making polynucleotide libraries, polynucleotide arrays, and cell libraries for high-throughput genomics analysis | CELL THERAPEUTICS, INC. | 2002-07-18 | — | — | US | disclosed |
| WO-2002053732-A2 | METHODS FOR MAKING POLYNUCLEOTIDE LIBRARIES, POLYNUCLEOTIDE ARRAYS, AND CELL LIBRRARIES FOR HIGH-THROUGHPUT GENOMICS ANALYSIS | PANGENEX (US) | 2002-07-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240374761-A1 | ANIMAL MODEL HAVING HOMOLOGOUS RECOMBINATION OF MOUSE PTH1 RECEPTOR | PTH1R, BMPR1A, PHPT1 | ALDH1A1 2747/4885LMNA 4076/4885MAPT 4617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.