Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 7/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6803422 | 0.79 | CTSS (0.52) | SMN1; SMN2EPHX1HPGDRAB9A | |
| SCHEMBL6802479 | 0.74 | CTSS (0.43) | HDAC6HPGDRAB9AMEN1ALDH1A1 | |
| SCHEMBL19954190 | 0.74 | MEP1B (0.51) | ROCK2CHRM2MMP13ROCK1PARP1 | |
| SCHEMBL6808965 | 0.72 | TSHR (0.47) | SMN1; SMN2RAB9AMEN1ALDH1A1KMT2A | |
| SCHEMBL6180760 | 0.71 | NPC1 (0.47) | HDAC6HPGDRAB9AALDH1A1KMT2A | |
| SCHEMBL6808215 | 0.70 | SLC6A9 (0.49) | ROCK2ROCK1PARP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6184297 | 0.70 | NMBR (0.40) | — | |
| SCHEMBL6807801 | 0.69 | KCNA5 (0.39) | HDAC6SMN1; SMN2MEN1ALDH1A1MAPK1 | |
| SCHEMBL13702363 | 0.68 | RAB9A (0.68) | ALOX15SMN1; SMN2HPGDRAB9AALDH1A1 | |
| SCHEMBL14863635 | 0.68 | L3MBTL1 (0.46) | HDAC6RAB9AMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063643-A1 | Bombesin antagonists | PFIZER INC. | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063643-A1 | Bombesin antagonists | BRS3, NPSR1, GNRHR | ROCK2 3753/4885CHRM2 253/4885MMP13 3219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.