Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL27816464 | 0.97 | STAT3 (0.40) | STAT3STAT1 | |
| Water SCHEMBL27896917 | 0.97 | STAT3 (0.40) | STAT3STAT1 | |
| Water SCHEMBL27572598 | 0.97 | STAT3 (0.40) | STAT3STAT1 | |
| Water SCHEMBL28471817 | 0.97 | STAT3 (0.40) | STAT3STAT1 | |
| Water SCHEMBL17868370 | 0.97 | STAT3 (0.40) | STAT3STAT1 | |
| Water SCHEMBL27703706 | 0.97 | STAT3 (0.40) | STAT3STAT1 | |
| SCHEMBL29430977 | 0.97 | STAT3 (0.42) | STAT3STAT1 | |
| SCHEMBL30821407 | 0.97 | STAT3 (0.42) | STAT3STAT1 | |
| SCHEMBL6744970 | 0.97 | STAT3 (0.42) | STAT3STAT1 | |
| Iodide SCHEMBL6766123 | 0.95 | STAT3 (0.39) | STAT3STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113827721-A | Application of nano material in preparation of medicine for treating atherosclerosis | 中国科学院宁波工业技术研究院慈溪生物医学工程研究所 | 2021-12-24 | — | — | CN | claimed |
| CN-1058388-C | Stable freeze dried polyhematoporphyrin ether/ester composition | QUADRA LOGIC TECH INC (CA) | 2000-11-15 | — | — | CN | claimed |
| CN-1047973-A | Stable freeze dried polyhematoporphyrin ether ether/ester composition | QUADRA LOGIC TECH INC (CA) | 1990-12-26 | — | — | CN | claimed |
| CN-120718691-A | Complex metal fuel catalytic regeneration additive component and preparation method and application thereof | 中国石油化工股份有限公司 | 2025-09-30 | — | — | CN | disclosed |
| CN-113827721-A | Application of nano material in preparation of medicine for treating atherosclerosis | 中国科学院宁波工业技术研究院慈溪生物医学工程研究所 | 2021-12-24 | — | — | CN | disclosed |
| CN-107075478-B | Method for preparing platelet product | 塞鲁斯公司 | 2021-11-09 | — | — | CN | disclosed |
| CN-109265465-B | Novel pyropheophorbide a derivatives and preparation method and application thereof | 陈志龙 | 2021-09-28 | — | — | CN | disclosed |
| CN-111770789-A | System and method for treating biological fluids | 塞鲁斯公司 | 2020-10-13 | — | — | CN | disclosed |
| CN-111655696-A | Compositions and methods for pathogen inactivation of platelets | 塞鲁斯公司 | 2020-09-11 | — | — | CN | disclosed |
| WO-2020015732-A1 | USES OF SULFOXIDE COMPOUND FOR PREVENTING NERVOUS SYSTEM DISEASES | 北京蔚蓝之源医药科技有限公司 | 2020-01-23 | — | — | WO | disclosed |
| WO-2020015731-A1 | USES OF SULFOXIDE COMPOUND FOR PREVENTING RADIATION-INDUCED ORAL MUCOSITIS AND RELATED RADIOTHERAPY COMPLICATIONS | 北京蔚蓝之源医药科技有限公司 | 2020-01-23 | — | — | WO | disclosed |
| CN-1081621-C | Amino substituted demethoxy hypocrellin and its preparing method | SENSITIVE CHEMISTRY INST CHINE (CN) | 2002-03-27 | — | — | CN | disclosed |
| US-20010049350-A1 | GROWTH INHIBITION AND ERADICATION OF SOLID TUMORS USING NEUROENDOCRINE RESETTING THERAPY AND PHOTODYNAMIC THERAPY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2001-12-06 | — | — | US | disclosed |
| EP-0910365-A4 | GROWTH INHIBITION AND ERADICATION OF SOLID TUMORS USING NEUROENDOCRINE RESETTING THERAPY AND PHOTODYNAMIC THERAPY | ERGO RESEARCH CORP (US) | 1999-12-01 | — | — | EP | disclosed |
| EP-0910365-A1 | GROWTH INHIBITION AND ERADICATION OF SOLID TUMORS USING NEUROENDOCRINE RESETTING THERAPY AND PHOTODYNAMIC THERAPY | Ergo Research Corporation (US) | 1999-04-28 | — | — | EP | disclosed |
| CN-1194263-A | Amino substituted demethoxy hypocrellin and its preparing method | SENSITIVE CHEMISTRY INST CHINE (CN) | 1998-09-30 | — | — | CN | disclosed |
| WO-1997040829-A9 | GROWTH INHIBITION AND ERADICATION OF SOLID TUMORS USING NEUROENDOCRINE RESETTING THERAPY AND PHOTODYNAMIC THERAPY | — | 1998-01-22 | — | — | WO | disclosed |
| WO-1997040829-A1 | GROWTH INHIBITION AND ERADICATION OF SOLID TUMORS USING NEUROENDOCRINE RESETTING THERAPY AND PHOTODYNAMIC THERAPY | ERGO RESEARCH CORPORATION (US) | 1997-11-06 | — | — | WO | disclosed |
| CN-1113914-A | Hematoporphyrin ether derivatives and their preparing method | NO 2 MILITARY MEDICAL COLLEGE (CN) | 1995-12-27 | — | — | CN | disclosed |
| WO-1991001727-A2 | METHOD OF DETECTION AND TREATMENT OF MALIGNANT AND NON-MALIGNANT LESIONS BY PHOTOCHEMOTHERAPY | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 1991-02-21 | — | — | WO | disclosed |