Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31059234 | 0.77 | FGF23 (0.40) | LMNASLC6A3SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL31059231 | 0.77 | FGF23 (0.40) | LMNASLC6A3SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL4320799 | 0.75 | BCL2L1 (0.43) | DHODHSLC6A3SLC6A4KMT2A | |
| SCHEMBL1551982 | 0.70 | GAA (0.39) | — | |
| SCHEMBL4350872 | 0.68 | SLC6A3 (0.65) | DHODHSLC6A3SLC6A2SLC6A4FABP4 | |
| SCHEMBL1751676 | 0.68 | SLC6A3 (0.65) | DHODHSLC6A3SLC6A2SLC6A4FABP4 | |
| SCHEMBL1751614 | 0.68 | SLC6A3 (0.65) | DHODHSLC6A3SLC6A2SLC6A4FABP4 | |
| SCHEMBL1752157 | 0.68 | SLC6A3 (0.65) | DHODHSLC6A3SLC6A2SLC6A4FABP4 | |
| SCHEMBL1751726 | 0.68 | SLC6A3 (0.60) | DHODHSLC6A3SLC6A2SLC6A4FABP4 | |
| SCHEMBL1752156 | 0.68 | SLC6A3 (0.65) | DHODHSLC6A3SLC6A2SLC6A4FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116398-A1 | Therapeutic applications of estrogenic carboxylic acids | SOUTHERN ILLINOIS UNIVERSITY | 2004-06-17 | — | — | US | claimed |
| WO-1999066915-A2 | THERAPEUTIC APPLICATIONS OF ESTROGENIC CARBOXYLIC ACIDS | SOUTHERN ILLINOIS UNIVERSITY AT CARBONDALE (US) | 1999-12-29 | — | — | WO | claimed |
| US-20040116398-A1 | Therapeutic applications of estrogenic carboxylic acids | SOUTHERN ILLINOIS UNIVERSITY | 2004-06-17 | — | — | US | disclosed |
| US-6608111-B1 | Estrogenic carboxylic acids; administering bisdehydrodoisynolic acid | SOUTHERN ILLINOIS UNIVERSITY OFFICE OF RESEARCH, DEVELOPMENT AND ADMINISTRATION | 2003-08-19 | — | — | US | disclosed |
| WO-1999066915-A2 | THERAPEUTIC APPLICATIONS OF ESTROGENIC CARBOXYLIC ACIDS | SOUTHERN ILLINOIS UNIVERSITY AT CARBONDALE (US) | 1999-12-29 | — | — | WO | disclosed |