Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR1 | P30872 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR1E | P28566 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | CDK4 | P11802 | 1/20 | 0.45 |
| ▸ | CCND1 | P24385 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6430387 | 0.88 | SSTR1 (0.63) | SSTR1HTR2AADRB1HTR1AADRA2A | |
| SCHEMBL1928394 | 0.88 | SSTR1 (0.63) | SSTR1HTR2AADRB1HTR1AADRA2A | |
| SCHEMBL4244351 | 0.88 | SSTR1 (0.63) | SSTR1HTR2AADRB1HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL27472186 | 0.87 | SSTR1 (0.62) | SSTR1HTR2AADRB1HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL6723717 | 0.87 | SSTR1 (0.62) | SSTR1HTR2AADRB1HTR1AADRA2A | |
| Hexane SCHEMBL27589497 | 0.84 | SSTR1 (0.56) | SSTR1HTR2AADRB1HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL1723213 | 0.82 | SSTR1 (0.53) | SSTR1HTR2AADRB1HTR1AADRA2A | |
| SCHEMBL13244865 | 0.82 | SSTR1 (0.53) | SSTR1HTR2AADRB1HTR1AADRA2A | |
| SCHEMBL3012885 | 0.82 | SSTR1 (0.53) | SSTR1HTR2AADRB1HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL27542605 | 0.82 | SSTR1 (0.53) | SSTR1HTR2AADRB1HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040132788-A1 | Derivatives of heterocycles with 5 members, their preparation and their use as medicaments | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040132788-A1 | Derivatives of heterocycles with 5 members, their preparation and their use as medicaments | OPRK1, HCN1, P2RX7 | SSTR1 1927/4885PTPN1 2447/4885HTR2A 665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.