SCHEMBL681183

SCHEMBL681183

CC1(C)CCCC(C)(C)N1OC(CO)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.40
OPRL1 P41146 1/20 0.35
PABPC1 P11940 1/20 0.35
APOBEC3A P31941 1/20 0.35
APOBEC3G Q9HC16 1/20 0.35
F9 P00740 1/20 0.34
F10 P00742 1/20 0.34
PLAU P00749 1/20 0.34
PRKG1 Q13976 1/20 0.34
SLC6A2 P23975 6/20 0.34
SLC6A3 Q01959 6/20 0.34
SLC6A4 P31645 2/20 0.34
USP2 O75604 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
KMT2A Q03164 1/20 0.33
OPRM1 P35372 1/20 0.33
OPRD1 P41143 1/20 0.33
BLM P54132 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15501122 1.00 GSR (0.40) GSROPRL1PABPC1APOBEC3AAPOBEC3G
SCHEMBL14390737 0.90 GSR (0.35) GSROPRL1PABPC1APOBEC3AAPOBEC3G
SCHEMBL12285713 0.88 GSR (0.33) GSROPRL1PABPC1APOBEC3AAPOBEC3G
SCHEMBL8439515 0.86 OPRM1 (0.35) OPRL1PABPC1APOBEC3AAPOBEC3GSLC6A3
SCHEMBL13168084 0.85 PABPC1 (0.33) OPRL1PABPC1APOBEC3AAPOBEC3GSLC6A2
SCHEMBL28343381 0.85 PABPC1 (0.35) OPRL1PABPC1APOBEC3AAPOBEC3GSLC6A2
SCHEMBL26289210 0.85 CHRNB2 (0.37) PABPC1APOBEC3AAPOBEC3GSLC6A4CYP3A4
SCHEMBL13683791 0.84 OPRM1 (0.38) OPRL1PABPC1APOBEC3AAPOBEC3GSLC6A2
SCHEMBL7781984 0.84 OPRM1 (0.32) OPRL1PABPC1APOBEC3AAPOBEC3GSLC6A2
SCHEMBL18642996 0.84 OPRM1 (0.40) OPRL1PABPC1APOBEC3AAPOBEC3GUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12539650-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-02-03 US claimed
EP-4514595-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2025-03-05 EP claimed
EP-4240578-B1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC (CH) 2024-12-18 EP claimed
US-11886045-B2 Method for making photochromic contact lenses ALCON INC. (CH) 2024-01-30 US claimed
WO-2023209570-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-02 WO claimed
US-20230339149-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-10-26 US claimed
EP-4240578-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES Alcon Inc. (CH) 2023-09-13 EP claimed
WO-2022097048-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2022-05-12 WO claimed
US-20220137433-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2022-05-05 US claimed
US-20260131506-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC (CH) 2026-05-14 US disclosed
US-12539650-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-02-03 US disclosed
EP-4514595-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2025-03-05 EP disclosed
EP-4240578-B1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC (CH) 2024-12-18 EP disclosed
US-11886045-B2 Method for making photochromic contact lenses ALCON INC. (CH) 2024-01-30 US disclosed
US-5866047-A Process for producing a shaped product MENICON CO., LTD. (JP) 1999-02-02 US disclosed
EP-0889918-A1 IN SITU BLOCK COPOLYMER FORMATION DURING POLYMERIZATION OF A VINYL AROMATIC MONOMER THE DOW CHEMICAL COMPANY (US) 1999-01-13 EP disclosed
EP-0889890-A1 NITROXYL CONTAINING COMPOUNDS THE DOW CHEMICAL COMPANY (US) 1999-01-13 EP disclosed
US-5721320-A In situ block copolymer formation during polymerization of a vinyl aromatic monomer THE DOW CHEMICAL COMPANY (US) 1998-02-24 US disclosed
WO-1997036894-A1 NITROXYL CONTAINING COMPOUNDS THE DOW CHEMICAL COMPANY (US) 1997-10-09 WO disclosed
WO-1997036944-A1 IN SITU BLOCK COPOLYMER FORMATION DURING POLYMERIZATION OF A VINYL AROMATIC MONOMER THE DOW CHEMICAL COMPANY (US) 1997-10-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12539650-B2 Method for making embedded hydrogel contact lenses INF2, CRYZ, CRYAA GSR 722/4885OPRL1 4689/4885PABPC1 4790/4885
US-20260131506-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES CRYZ, CRYAB, CRYAA GSR 288/4885OPRL1 4745/4885PABPC1 4429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.