Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6809479 | 0.83 | POLB (0.42) | APPCNR1CNR2ATMTDP1 | |
| SCHEMBL6808979 | 0.78 | ATM (0.59) | CNR1CNR2ATMTDP1L3MBTL1 | |
| SCHEMBL6812421 | 0.72 | TUBB4A (0.57) | APPCNR1CNR2ATMTDP1 | |
| SCHEMBL27567027 | 0.69 | TDP1 (0.50) | APPATMTDP1IKBKBMEN1 | |
| SCHEMBL3491387 | 0.68 | ABL1 (0.52) | APPATMTDP1IKBKBMEN1 | |
| SCHEMBL4724741 | 0.68 | KDM4E (0.53) | APPCNR1CNR2ATMTDP1 | |
| SCHEMBL6808984 | 0.68 | TUBB4A (0.46) | CNR1CNR2ATMTDP1L3MBTL1 | |
| SCHEMBL21797208 | 0.67 | CES2 (0.47) | APPCNR1CNR2ATMTDP1 | |
| SCHEMBL6597757 | 0.66 | L3MBTL1 (0.59) | CNR1CNR2ATMTDP1L3MBTL1 | |
| SCHEMBL28515985 | 0.66 | TDP1 (0.59) | CNR1CNR2ATMTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040044224-A1 | Process for preparing 2-phenyl-3-aminobenzothiophenes | CONRAD PRESTON CHARLES (US) | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044224-A1 | Process for preparing 2-phenyl-3-aminobenzothiophenes | TPST2, SULT1A1, TYR | APP 441/4885CNR1 4658/4885CNR2 4619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.