Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6811980 | 0.83 | APP (0.45) | APPMEN1KMT2AATML3MBTL1 | |
| SCHEMBL8143138 | 0.74 | KDM4E (0.57) | GAAMEN1KMT2AATML3MBTL1 | |
| SCHEMBL7689092 | 0.74 | POLB (0.49) | POLBGAAMEN1KMT2AADORA1 | |
| SCHEMBL6808979 | 0.74 | ATM (0.59) | GAAMEN1KMT2AATML3MBTL1 | |
| SCHEMBL316475 | 0.70 | KDM4E (0.56) | POLBGAAAPPMEN1KMT2A | |
| SCHEMBL16690782 | 0.70 | APP (0.50) | GAAAPPMEN1KMT2AL3MBTL1 | |
| SCHEMBL6812421 | 0.68 | TUBB4A (0.57) | APPMEN1KMT2AATML3MBTL1 | |
| SCHEMBL6951995 | 0.66 | ESR2 (0.59) | POLBGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL21896646 | 0.66 | MAP2K1 (0.41) | GAAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL8158192 | 0.65 | TUBB4A (0.53) | MEN1KMT2AATML3MBTL1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040044224-A1 | Process for preparing 2-phenyl-3-aminobenzothiophenes | CONRAD PRESTON CHARLES (US) | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044224-A1 | Process for preparing 2-phenyl-3-aminobenzothiophenes | TPST2, SULT1A1, TYR | POLB 529/4885GAA 1634/4885APP 441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.