Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.61 |
| ▸ | DRD3 | P35462 | 11/20 | 0.61 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.61 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24719093 | 1.00 | DRD2 (0.61) | DRD2DRD3ADRB1NOTUMALDH1A1 | |
| SCHEMBL30890968 | 1.00 | DRD2 (0.61) | DRD2DRD3ADRB1NOTUMALDH1A1 | |
| SCHEMBL6812356 | 0.85 | ALDH1A1 (0.49) | DRD2DRD3ADRB1NOTUMALDH1A1 | |
| SCHEMBL8511 | 0.76 | DRD2 (1.00) | DRD2DRD3ADRB1ALDH1A1LMNA | |
| SCHEMBL6352699 | 0.76 | DRD2 (1.00) | DRD2DRD3ADRB1ALDH1A1LMNA | |
| SCHEMBL29367982 | 0.76 | DRD2 (1.00) | DRD2DRD3ADRB1ALDH1A1LMNA | |
| SCHEMBL1904488 | 0.76 | ALDH1A1 (0.63) | NOTUMALDH1A1LMNABIRC2HTR2C | |
| SCHEMBL1901041 | 0.76 | ALDH1A1 (0.63) | NOTUMALDH1A1LMNABIRC2HTR2C | |
| SCHEMBL1901039 | 0.76 | ALDH1A1 (0.63) | NOTUMALDH1A1LMNABIRC2HTR2C | |
| SCHEMBL12164853 | 0.76 | ADRB1 (0.63) | ADRB1ALDH1A1LMNAHTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002364-A1 | BENZOTHIOPHENE DERIVATIVE REGULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2023-01-05 | — | — | US | disclosed |
| EP-4056568-A1 | BENZOTHIOPHENE DERIVATIVE REGULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2022-09-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002364-A1 | BENZOTHIOPHENE DERIVATIVE REGULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | GPER1, GABRQ, GPR39 | DRD2 1191/4885DRD3 1822/4885ADRB1 206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.