Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | ATM | Q13315 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA5A | P35218 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.57 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1029558 | 0.98 | CHRM2 (0.59) | CHRM2CHRM1CHRM3KDM4ELMNA | |
| Formaldehyde SCHEMBL12492240 | 0.94 | SMN1; SMN2 (0.59) | CHRM2CHRM1CHRM3KDM4ELMNA | |
| SCHEMBL4615272 | 0.88 | CALM1 (0.58) | KDM4ELMNASMN1; SMN2POLBHTT | |
| Hydrochloric Acid SCHEMBL4615416 | 0.86 | MEN1 (0.60) | KDM4ELMNASMN1; SMN2POLBHTT | |
| SCHEMBL28661867 | 0.84 | SMN1; SMN2 (0.65) | CHRM2KDM4ELMNASMN1; SMN2ATM | |
| SCHEMBL13886531 | 0.84 | SIGMAR1 (0.61) | CHRM2KDM4ELMNASMN1; SMN2POLB | |
| Trifluoroacetic Acid SCHEMBL5072989 | 0.83 | SMN1; SMN2 (0.56) | SMN1; SMN2ATMTAAR1ALDH1A1F2RL1 | |
| SCHEMBL10156581 | 0.83 | TAAR1 (0.76) | CHRM2CHRM1CHRM3KDM4ELMNA | |
| SCHEMBL9667596 | 0.83 | CHRM2 (0.67) | CHRM2CHRM1CHRM3KDM4ELMNA | |
| SCHEMBL17331156 | 0.83 | TAAR1 (0.75) | KDM4ELMNASMN1; SMN2HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 641 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260000678-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING, SUPPRESSING, OR TREATING SYMPTOM ASSOCIATED WITH PSEUDO-ALLERGIC REACTION | TAKASAKI UNIV OF HEALTH AND WELFARE (JP) | 2026-01-01 | — | — | US | claimed |
| EP-4583860-A1 | INHIBITORS OF THE CERAMIDE METABOLIC PATHWAY FOR OVERCOMING IMMUNOTHERAPY RESISTANCE IN CANCER | Institut National de la Santé et de la Recherche Médicale (FR) | 2025-07-16 | — | — | EP | claimed |
| EP-4501357-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR SUPPRESSING OR TREATING SYMPTOMS ACCOMPANYING PSEUDO-ALLERGIC REACTIONS | Takasaki University of Health and Welfare (JP) | 2025-02-05 | — | — | EP | claimed |
| CN-119233829-A | Pharmaceutical composition for preventing, inhibiting or treating symptoms associated with pseudoallergy | 学校法人高崎健康福祉大学 | 2024-12-31 | — | — | CN | claimed |
| CN-119143633-A | Nitrobenzene-containing urea compound and preparation method and application thereof | 西安交通大学 | 2024-12-17 | — | — | CN | claimed |
| CN-118599773-A | Immune cell-based raw material screening model and screening of sensitive muscle raw materials by using same | 广州市华代生物科技有限公司 | 2024-09-06 | — | — | CN | claimed |
| CN-118477091-A | Lnc-MSTRG.32352.2 and application thereof | 河北大学 | 2024-08-13 | — | — | CN | claimed |
| CN-118421747-A | Combined method for evaluating in-vitro soothing efficacy of cosmetic raw materials | 云南贝泰妮生物科技集团股份有限公司 | 2024-08-02 | — | — | CN | claimed |
| US-20240252610-A1 | A BROADLY PROTECTIVE PROPHYLACTIC VACCINE AGAINST PSEUDOMONAS AERUGINOSA | UNIVERSITY OF MARYLAND, BALTIMORE | 2024-08-01 | — | — | US | claimed |
| EP-4340872-A2 | A BROADLY PROTECTIVE PROPHYLACTIC VACCINE AGAINST PSEUDOMONAS AERUGINOSA | University of Kansas (US) | 2024-03-27 | — | — | EP | claimed |
| CN-114295535-A | Method for rapidly detecting soothing effect of cosmetics through mast cell degranulation state | 常州市艾斯康生物医药有限公司 | 2022-04-08 | — | — | CN | claimed |
| EP-2119363-B1 | Enhanced antimicrobial activity of plant essential oils | VAN BEEK RONALD R (US) | 2019-01-09 | — | — | EP | claimed |
| EP-1501830-B1 | 7-ARYL-3,9-DIAZABICYCLO[3.3.1]NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES | ACTELION PHARMACEUTICALS LTD (CH) | 2011-10-05 | — | — | EP | claimed |
| US-20080312242-A1 | 7-ARYL-3, 9-DIAZABICYCLO(3.3.1)NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES | ACTELION PHARMACEUTICALS, LTD. (CH) | 2008-12-18 | — | — | US | claimed |
| US-7427613-B2 | 7-aryl-3,9-diazabicyclo(3.3.1)non-6-ene derivatives and their use as renin inhibitors in the treatment of hypertension, cardiovascular or renal diseases | ACTELION PHARMACEUTICALS LTD. (CH) | 2008-09-23 | — | — | US | claimed |
| US-20050176700-A1 | 7-aryl-3,9-diazabicyclo(3.3.1)non-6-ene derivatives and their use as renin inhibitors in the treatment of hypertension,cardiovascular or renal diseases | ACTELION PHARMACEUTICALS LTD. (CH) | 2005-08-11 | — | — | US | claimed |
| EP-1501830-A1 | 7-ARYL-3,9-DIAZABICYCLO[3.3.1]NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES | Actelion Pharmaceuticals Ltd. (CH) | 2005-02-02 | — | — | EP | claimed |
| WO-2003093267-A1 | 7-ARYL-3,9-DIAZABICYCLO(3.3.1)NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES | ACTELION PHARMACEUTICALS LTD (CH) | 2003-11-13 | — | — | WO | claimed |
| EP-0308456-B1 | COMPOSITON FOR THE TREATMENT OF THE EPIDERM | SCHOEFF, Nadine (FR) | 1991-12-04 | — | — | EP | claimed |
| US-4996057-A | Human placental tissue proteins and a condensation product of n-methyl-p-methoxyphenethylamine with formaldehyde; hair growth | Schoeff, Nadine (FR) | 1991-02-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176700-A1 | 7-aryl-3,9-diazabicyclo(3.3.1)non-6-ene derivatives and their use as renin inhibitors in the treatment of hypertension,cardiovascular or renal diseases | REN, AGTR1, ACE | CHRM2 3509/4885CHRM1 2464/4885CHRM3 2273/4885 |
| US-20260000678-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING, SUPPRESSING, OR TREATING SYMPTOM ASSOCIATED WITH PSEUDO-ALLERGIC REACTION | TRPV1, TRPV4, TRPV5 | CHRM2 790/4885CHRM1 533/4885CHRM3 286/4885 |
| US-20080312242-A1 | 7-ARYL-3, 9-DIAZABICYCLO(3.3.1)NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES | REN, AGTR1, ACE | CHRM2 3509/4885CHRM1 2464/4885CHRM3 2273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.