Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818637 | 0.88 | RAB9A (0.47) | RAB9ASMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL6821049 | 0.84 | MAPT (0.59) | RAB9ASMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL6818333 | 0.82 | NPC1 (0.69) | RAB9ASMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL5465423 | 0.81 | PDGFRB (0.53) | RAB9ASMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL6818334 | 0.81 | ALDH1A1 (0.52) | SMN1; SMN2MEN1KMT2AALDH1A1HTT | |
| SCHEMBL2435686 | 0.76 | ALDH1A1 (0.55) | ALDH1A1MAPTGAATSHR | |
| SCHEMBL31170840 | 0.76 | ALDH1A1 (0.59) | SMN1; SMN2LMNAPOLBALDH1A1MAPT | |
| SCHEMBL286994 | 0.76 | ALDH1A1 (0.59) | SMN1; SMN2LMNAPOLBALDH1A1MAPT | |
| SCHEMBL7423042 | 0.74 | GAA (0.51) | LMNAPOLBALDH1A1MAPTGAA | |
| SCHEMBL7426294 | 0.74 | ALDH1A1 (0.46) | RAB9ASMN1; SMN2KMT2ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046122-A2 | BENZOXAZOLE, BENZTHIAZOLE AND BENZIMIDAZOLE ACID DERIVATIVES AND THEIR USE AS HEPARANASE INHIBITORS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2004-06-03 | — | — | WO | disclosed |