Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 8/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.63 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.63 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.63 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.63 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.63 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.63 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | THRA | P10827 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6821049 | 0.88 | MAPT (0.59) | NPC1RAB9AMEN1KMT2APABPC1 | |
| SCHEMBL6818294 | 0.82 | RAB9A (0.53) | NPC1RAB9AMEN1KMT2APABPC1 | |
| SCHEMBL6818426 | 0.81 | KMT2A (0.56) | NPC1RAB9AMEN1KMT2AHTT | |
| SCHEMBL6821342 | 0.81 | KCNMA1 (0.56) | NPC1MEN1KMT2APABPC1DUSP3 | |
| SCHEMBL6822188 | 0.81 | KCNMA1 (0.51) | NPC1RAB9AMEN1KMT2APABPC1 | |
| SCHEMBL6818637 | 0.81 | RAB9A (0.47) | NPC1RAB9AMEN1KMT2APABPC1 | |
| SCHEMBL520733 | 0.79 | MEN1 (0.58) | RAB9AMEN1KMT2AHTTMAPT | |
| SCHEMBL6818334 | 0.79 | ALDH1A1 (0.52) | MEN1KMT2AHTTALDH1A1CYP3A4 | |
| SCHEMBL22347296 | 0.78 | RAB9A (0.81) | NPC1RAB9AMEN1KMT2APABPC1 | |
| SCHEMBL8720282 | 0.78 | MEN1 (0.58) | MEN1KMT2AHTTTHRAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046122-A2 | BENZOXAZOLE, BENZTHIAZOLE AND BENZIMIDAZOLE ACID DERIVATIVES AND THEIR USE AS HEPARANASE INHIBITORS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2004-06-03 | — | — | WO | disclosed |