Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.54 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.54 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.54 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.54 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.52 |
| ▸ | CCR5 | P51681 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818333 | 0.88 | NPC1 (0.69) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL6818294 | 0.84 | RAB9A (0.53) | MAPTRAB9ANPC1LMNAMEN1 | |
| SCHEMBL6818637 | 0.84 | RAB9A (0.47) | MAPTRAB9ANPC1LMNAMEN1 | |
| SCHEMBL6818426 | 0.84 | KMT2A (0.56) | MAPTRAB9ANPC1LMNAMEN1 | |
| SCHEMBL6822188 | 0.84 | KCNMA1 (0.51) | MAPTRAB9ANPC1LMNAMEN1 | |
| SCHEMBL6821342 | 0.84 | KCNMA1 (0.56) | MAPTNPC1LMNAMEN1KMT2A | |
| SCHEMBL6818334 | 0.80 | ALDH1A1 (0.52) | MEN1KMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7377697 | 0.79 | RAB9A (0.68) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL521069 | 0.78 | MAPT (0.57) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL31499386 | 0.77 | RAB9A (0.65) | MAPTRAB9ANPC1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046122-A2 | BENZOXAZOLE, BENZTHIAZOLE AND BENZIMIDAZOLE ACID DERIVATIVES AND THEIR USE AS HEPARANASE INHIBITORS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2004-06-03 | — | — | WO | disclosed |