Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818294 | 0.81 | RAB9A (0.53) | ALDH1A1HTTMEN1KMT2AL3MBTL1 | |
| SCHEMBL6821342 | 0.80 | KCNMA1 (0.56) | ALDH1A1KCNMA1HTTMEN1KMT2A | |
| SCHEMBL6822188 | 0.80 | KCNMA1 (0.51) | ALDH1A1KCNMA1HTTMEN1KMT2A | |
| SCHEMBL6818426 | 0.80 | KMT2A (0.56) | ALDH1A1KCNMA1HTTMEN1KMT2A | |
| SCHEMBL6818637 | 0.80 | RAB9A (0.47) | ALDH1A1MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL6821049 | 0.80 | MAPT (0.59) | ALDH1A1KCNMA1HTTMEN1KMT2A | |
| SCHEMBL6818333 | 0.79 | NPC1 (0.69) | ALDH1A1HTTABCG2MEN1KMT2A | |
| SCHEMBL286994 | 0.78 | ALDH1A1 (0.59) | ALDH1A1HPGDCYP2C19L3MBTL1GAA | |
| SCHEMBL31170840 | 0.78 | ALDH1A1 (0.59) | ALDH1A1HPGDCYP2C19L3MBTL1GAA | |
| SCHEMBL28069367 | 0.76 | KCNMA1 (0.78) | ALDH1A1KCNMA1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046122-A2 | BENZOXAZOLE, BENZTHIAZOLE AND BENZIMIDAZOLE ACID DERIVATIVES AND THEIR USE AS HEPARANASE INHIBITORS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2004-06-03 | — | — | WO | disclosed |