Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6817272 | 0.86 | OPRM1 (0.34) | HTTKMT2A | |
| SCHEMBL6823713 | 0.83 | LMNA (0.39) | HTTMEN1KMT2A | |
| SCHEMBL6820669 | 0.78 | OPRM1 (0.34) | HTTKMT2A | |
| SCHEMBL6821070 | 0.74 | APOL1 (0.36) | HTTMEN1KMT2ARORC | |
| SCHEMBL6817250 | 0.72 | SMN1; SMN2 (0.38) | HTTMEN1KMT2A | |
| SCHEMBL5963669 | 0.69 | CHRNB2 (0.37) | CHRNB2CHRNB4CHRNA3CHRNA4HTT | |
| SCHEMBL8425193 | 0.60 | BACE1 (0.54) | MEN1KMT2ARORCPSEN1PSEN2 | |
| SCHEMBL10264321 | 0.58 | LSS (0.56) | TRPV1MEN1KMT2A | |
| SCHEMBL16838991 | 0.58 | SSTR3 (0.44) | TRPV1MEN1KMT2ATRPM2 | |
| SCHEMBL5963783 | 0.57 | SLC6A4 (0.33) | SLC6A4SLC6A3MEN1KMT2AP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326851-B1 | SUBSTITUTED DIPEPTIDES AS GROWTH HORMONE SECRETAGOGUES | LILLY CO ELI (US) | 2004-06-30 | — | — | EP | claimed |