Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | NR1D2 | Q14995 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5963561 | 0.88 | SLC6A2 (0.33) | SLC6A4SLC6A3SLC6A2KCNH2LMNA | |
| SCHEMBL6821070 | 0.70 | APOL1 (0.36) | MEN1ALDH1A1TSHRKMT2AOPRM1 | |
| SCHEMBL5963669 | 0.69 | CHRNB2 (0.37) | SLC6A4SLC6A3SLC6A2KCNH2GALR1 | |
| SCHEMBL5964213 | 0.69 | HSD11B1 (0.33) | SLC6A4SLC6A3SLC6A2LMNADRD2 | |
| SCHEMBL5001010 | 0.66 | CACNA1G (0.38) | ALDH1A1KMT2ADRD2SIGMAR1 | |
| SCHEMBL5963662 | 0.66 | ADORA2B (0.35) | SLC6A4SLC6A3SLC6A2MEN1ALDH1A1 | |
| SCHEMBL5963922 | 0.66 | GALR1 (0.38) | SLC6A4SLC6A3SLC6A2KCNH2MEN1 | |
| SCHEMBL5964017 | 0.65 | GRIN1 (0.36) | SLC6A4SLC6A3SLC6A2KCNH2ALDH1A1 | |
| SCHEMBL5004773 | 0.63 | ALDH1A1 (0.36) | SLC6A4SLC6A3MEN1ALDH1A1KMT2A | |
| SCHEMBL6820982 | 0.62 | KDM4E (0.36) | SLC6A2ALDH1A1LMNADRD2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7125840-B2 | Substituted dipeptides as growth hormone secretagogues | ELI LILLY AND COMPANY (US) | 2006-10-24 | — | — | US | disclosed |
| US-20040058971-A1 | Substituted dipeptides as growth hormone secretagogues | ELI LILLY AND COMPANY | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058971-A1 | Substituted dipeptides as growth hormone secretagogues | GHSR, GHRHR, SSTR4 | SLC6A4 794/4885SLC6A3 981/4885SLC6A2 1380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.