Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 12/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 4/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820218 | 0.87 | UTS2R (0.44) | KMT2AUTS2R | |
| SCHEMBL6820985 | 0.85 | KMT2A (0.56) | PLA2G2ATSHRMAPK1KMT2AHTR6 | |
| SCHEMBL6820977 | 0.78 | HTR6 (0.53) | PLA2G2AHTR6UTS2RHTR2A | |
| SCHEMBL3563162 | 0.78 | HTR6 (0.54) | KMT2AHTR6HTR2A | |
| SCHEMBL6823545 | 0.78 | UTS2R (0.41) | TSHRKMT2AUTS2R | |
| SCHEMBL6823922 | 0.77 | CNR1 (0.47) | PLA2G2ATSHRKMT2AHTR6 | |
| SCHEMBL6820693 | 0.76 | UTS2R (0.46) | UTS2R | |
| SCHEMBL6822016 | 0.76 | UTS2R (0.39) | TSHRKMT2AUTS2R | |
| SCHEMBL6821006 | 0.75 | TDP1 (0.52) | PLA2G2ATSHRMAPK1KMT2A | |
| SCHEMBL3560474 | 0.74 | HTR6 (0.52) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |