Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3557475 | 0.90 | HTR6 (0.45) | HTR6LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6821009 | 0.89 | AGTR1 (0.46) | HTR6LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6817298 | 0.88 | LMNA (0.61) | HTR6LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6817324 | 0.88 | HTR6 (0.43) | HTR6LMNACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6820229 | 0.87 | ALDH1A1 (0.43) | HTR6LMNAKMT2APTGS2MEN1 | |
| SCHEMBL6919614 | 0.87 | PTGS2 (0.46) | HTR6KMT2APTGS2MEN1 | |
| SCHEMBL6821037 | 0.81 | ABCB1 (0.43) | HTR6KMT2APTGS2MEN1 | |
| SCHEMBL6922144 | 0.78 | ESR1 (0.51) | HTR6TSHRPLA2G2AKMT2A | |
| SCHEMBL3558463 | 0.78 | HTR6 (0.60) | HTR6 | |
| SCHEMBL3555919 | 0.76 | KDM4E (0.45) | CYP1A2CYP2D6KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |