Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 4/20 | 0.44 |
| ▸ | PPIB | P23284 | 1/20 | 0.44 |
| ▸ | PPIA | P62937 | 1/20 | 0.44 |
| ▸ | PPIG | Q13427 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818212 | 0.80 | PPID (0.41) | PPIDPPIBPPIAPPIGALDH1A1 | |
| SCHEMBL1732616 | 0.79 | SMN1; SMN2 (0.49) | ALDH1A1GAAKMT2ALMNAMEN1 | |
| SCHEMBL14020496 | 0.79 | L3MBTL1 (0.47) | ALDH1A1GAAL3MBTL1KMT2ALMNA | |
| SCHEMBL6818574 | 0.78 | SMN1; SMN2 (0.52) | ALDH1A1GAALMNACA2CA1 | |
| SCHEMBL31748328 | 0.74 | RAB9A (0.45) | ALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL13516999 | 0.72 | PPID (0.48) | PPIDPPIBPPIAPPIGALDH1A1 | |
| SCHEMBL6821786 | 0.72 | ALDH1A1 (0.43) | ALDH1A1GAAL3MBTL1KMT2ACA2 | |
| SCHEMBL6821787 | 0.72 | ALDH1A1 (0.43) | ALDH1A1GAAL3MBTL1KMT2ACA2 | |
| SCHEMBL6821770 | 0.71 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1KMT2AMEN1TSHR | |
| SCHEMBL6821734 | 0.70 | PPID (0.65) | PPIDPPIBPPIAPPIGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050646-A1 | 1, 2, 5-THIADIAZOLIDIN-3-ONE 1, 1 DIOXIDE DERIVATIVES AS INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE PTP1B | ASTRAZENECA AB (SE) | 2004-06-17 | — | — | WO | disclosed |