Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 16/20 | 0.57 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.56 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820689 | 0.84 | PLA2G2A (0.68) | PLA2G2APLA2G1BKMT2ATSHRMAPK1 | |
| SCHEMBL6821169 | 0.83 | KMT2A (0.52) | PLA2G2AKMT2ATSHRMAPK1MAPT | |
| SCHEMBL6918963 | 0.81 | KDR (0.50) | KMT2ATSHRMAPT | |
| SCHEMBL6920117 | 0.80 | CA12 (0.48) | PLA2G2AKMT2AMAPT | |
| SCHEMBL6821059 | 0.80 | MAPT (0.48) | KMT2AMAPTNTRK1 | |
| SCHEMBL6820233 | 0.79 | CYP19A1 (0.59) | KMT2AMAPK1MAPTNTRK1 | |
| SCHEMBL9017573 | 0.79 | PLA2G2A (0.74) | PLA2G2APLA2G1BKMT2ATSHRMAPK1 | |
| SCHEMBL3855197 | 0.78 | GRIK2 (0.64) | PLA2G2AGRIK2PLA2G1BKMT2ATSHR | |
| SCHEMBL6922144 | 0.77 | ESR1 (0.51) | PLA2G2AGRIK2PLA2G1BKMT2ATSHR | |
| SCHEMBL6920467 | 0.76 | PLA2G2A (0.55) | PLA2G2APLA2G1BKMT2ATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |