Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HK1 | P19367 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.44 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | CD74 | P04233 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6823487 | 0.87 | MDM2 (0.48) | MAPTKDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL6918963 | 0.84 | KDR (0.50) | MAPTALDH1A1KDM4EHSD17B10SRC | |
| SCHEMBL6821169 | 0.83 | KMT2A (0.52) | MAPTHTTALDH1A1KDM4EGAA | |
| SCHEMBL6920117 | 0.83 | CA12 (0.48) | MAPTALDH1A1KDM4EGAASRC | |
| SCHEMBL6820233 | 0.82 | CYP19A1 (0.59) | MAPTHTTALDH1A1KDM4EGAA | |
| SCHEMBL6821058 | 0.80 | PLA2G2A (0.57) | MAPTKMT2ANTRK1 | |
| SCHEMBL6820929 | 0.76 | KDR (0.46) | MAPTHTTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL6923669 | 0.74 | SRC (0.50) | MAPTHK1HTTHKDC1ALDH1A1 | |
| SCHEMBL28107204 | 0.73 | CYP11B2 (0.59) | MAPTHK1HTTHKDC1ALDH1A1 | |
| SCHEMBL10067377 | 0.72 | MAPT (0.57) | MAPTHK1HTTHKDC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |