Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.56 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 2/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | VEGFA | P15692 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2196501 | 0.86 | CYP19A1 (0.71) | CYP19A1ALDH1A1SMN1; SMN2GRM5 | |
| SCHEMBL2425876 | 0.83 | CYP3A4 (0.50) | CYP19A1CHRNB2CHRNA4ALDH1A1GRM5 | |
| SCHEMBL876009 | 0.79 | CYP19A1 (0.45) | CYP19A1ALDH1A1SMN1; SMN2GRM5CYP3A4 | |
| SCHEMBL876496 | 0.79 | LTA4H (0.46) | CYP19A1LTA4HGRM5CYP3A4VEGFA | |
| Water SCHEMBL29061097 | 0.77 | PGR (0.55) | CYP19A1LTA4HTSHRCHEK2ALDH1A1 | |
| SCHEMBL7186441 | 0.77 | PGR (0.55) | CYP19A1LTA4HTSHRCHEK2ALDH1A1 | |
| SCHEMBL30358273 | 0.77 | PGR (0.55) | CYP19A1LTA4HTSHRCHEK2ALDH1A1 | |
| SCHEMBL12458014 | 0.77 | MAOB (0.63) | CHRNB2CHRNA4SMN1; SMN2 | |
| Diphenylether SCHEMBL4188767 | 0.76 | TSHR (0.70) | CYP19A1LTA4HTSHRCHEK2SMN1; SMN2 | |
| SCHEMBL23087866 | 0.76 | GRM5 (0.46) | CYP19A1ALDH1A1SMN1; SMN2GRM5VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | CYP19A1 869/4885LTA4H 1376/4885TSHR 3622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.