Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 7/20 | 0.51 |
| ▸ | CTSS | P25774 | 5/20 | 0.51 |
| ▸ | CTSB | P07858 | 5/20 | 0.51 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | FPR2 | P25090 | 5/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | FPR1 | P21462 | 3/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6822298 | 0.93 | CTSS (0.44) | CTSLCTSSCTSBCTSKLCK | |
| SCHEMBL6020162 | 0.90 | CTSL (0.61) | CTSLCTSSCTSBCTSKLCK | |
| SCHEMBL6020864 | 0.84 | PTGS2 (0.47) | CTSLCTSSCTSB | |
| SCHEMBL6822629 | 0.84 | CTSS (0.51) | CTSLCTSSCTSBCTSKLCK | |
| SCHEMBL6448627 | 0.84 | CA1 (0.40) | CTSLCTSSCTSBFPR2 | |
| SCHEMBL6020835 | 0.83 | CTSB (0.67) | CTSLCTSSCTSBCTSK | |
| SCHEMBL6818830 | 0.83 | CTSL (0.54) | CTSLCTSSCTSBCTSKFPR2 | |
| SCHEMBL6021024 | 0.83 | CTSB (0.66) | CTSLCTSSCTSBCTSK | |
| SCHEMBL6020791 | 0.82 | CTSS (0.55) | CTSLCTSSCTSBCTSKLCK | |
| SCHEMBL6449677 | 0.81 | FPR2 (0.52) | CTSLCTSSCTSBCTSKFPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004056755-A2 | COMPOUNDS FOR THE INHIBITION OF NON-PROTEOLYTIC ENZYMES | JERENI AG (DE) | 2004-07-08 | — | — | WO | claimed |
| WO-2004056755-A2 | COMPOUNDS FOR THE INHIBITION OF NON-PROTEOLYTIC ENZYMES | JERENI AG (DE) | 2004-07-08 | — | — | WO | disclosed |