SCHEMBL6823243

SCHEMBL6823243

CC(=O)NCc1ccc(CN(NCl)C(=O)N(C)C2CCCC2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.40
MAPT P10636 3/20 0.40
ALDH1A1 P00352 1/20 0.40
POLB P06746 1/20 0.40
KMT2A Q03164 4/20 0.40
MEN1 O00255 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
GAA P10253 2/20 0.39
HDAC1 Q13547 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
ACACB O00763 1/20 0.38
HSD11B1 P28845 1/20 0.37
HSD11B2 P80365 1/20 0.37
HPGD P15428 1/20 0.36
NPC1 O15118 1/20 0.36
EPHX1 P07099 1/20 0.36
HRH4 Q9H3N8 1/20 0.36
HRH3 Q9Y5N1 1/20 0.36
CCR5 P51681 1/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6823240 0.82 RAB9A (0.41) RAB9AMAPTALDH1A1POLBKMT2A
SCHEMBL6823012 0.73 NPSR1 (0.42) RAB9AMAPTALDH1A1POLBKMT2A
SCHEMBL7977518 0.70 KMT2A (0.59) RAB9AMAPTALDH1A1POLBKMT2A
SCHEMBL6823784 0.69 NOS3 (0.46) RAB9AMAPTALDH1A1POLBKMT2A
SCHEMBL23680337 0.68 MEN1 (0.58) RAB9AALDH1A1POLBKMT2AMEN1
SCHEMBL469040 0.68 HTR2C (0.58) RAB9AMAPTALDH1A1POLBKMT2A
SCHEMBL12133623 0.67 KMT2A (0.76) RAB9AMAPTALDH1A1POLBKMT2A
SCHEMBL16894163 0.65 MAPK1 (0.59) RAB9AALDH1A1KMT2AMEN1HPGD
SCHEMBL12001266 0.64 ACACB (0.52) ALDH1A1KMT2AACACB
SCHEMBL9242992 0.64 ALDH1A1 (0.61) RAB9AMAPTALDH1A1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004067522-A1 AZAPHENYLALANINE DERIVATIVES AND THEIR USE AS ANTITHROMBOTIC AGENTS LEK PHARMACEUTICALS D.D. (SI) 2004-08-12 WO disclosed