Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 2/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.36 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5761337 | 0.72 | ALDH1A1 (0.35) | NR1I2SMARCA2SMARCA4PBRM1POLB | |
| SCHEMBL5756540 | 0.72 | ALDH1A1 (0.35) | NR1I2SMARCA2SMARCA4PBRM1POLB | |
| Hydrochloric Acid SCHEMBL5754916 | 0.70 | ALDH1A1 (0.34) | NR1I2SMARCA2SMARCA4PBRM1POLB | |
| SCHEMBL5759783 | 0.69 | NR1I2 (0.33) | NR1I2SMARCA2SMARCA4PBRM1POLB | |
| SCHEMBL15301290 | 0.68 | KEAP1 (0.48) | NR1I2SMARCA2SMARCA4PBRM1POLB | |
| Hydrochloric Acid SCHEMBL5754089 | 0.68 | NR1I2 (0.33) | NR1I2SMARCA2SMARCA4PBRM1POLB | |
| SCHEMBL188043 | 0.68 | GPR55 (0.44) | POLBALDH1A1KEAP1NPC1MAPK1 | |
| SCHEMBL14283829 | 0.68 | FYN (0.43) | NR1I2SMARCA2SMARCA4PBRM1POLB | |
| SCHEMBL28777073 | 0.67 | POLB (0.40) | NR1I2SMARCA2SMARCA4PBRM1POLB | |
| SCHEMBL19986733 | 0.64 | ADRB2 (0.67) | POLBALDH1A1CHRNB2CHRNA4CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6676932-B2 | CONTAINING PYRIDAZINE DERIVATIVE SUNSCREEN AGENT | SHISEIDO CO., LTD. (JP) | 2004-01-13 | — | — | US | disclosed |