Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 12/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 10/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828221 | 0.91 | LMNA (0.57) | TP53LMNAPOLBMAPTSMN1; SMN2 | |
| SCHEMBL6825631 | 0.89 | LMNA (0.58) | EPHX2TP53LMNAPOLBMAPT | |
| SCHEMBL6828555 | 0.88 | SMN1; SMN2 (0.70) | EPHX2NR1H4TP53LMNAPOLB | |
| SCHEMBL6828200 | 0.81 | ROCK2 (0.57) | LMNAPOLBSMN1; SMN2 | |
| SCHEMBL6825305 | 0.80 | ALDH1A1 (0.52) | EPHX2TP53LMNAPOLBMAPT | |
| SCHEMBL6825524 | 0.78 | HTT (0.66) | TP53LMNAPOLBMAPTSMN1; SMN2 | |
| SCHEMBL6825586 | 0.76 | MAPT (0.58) | LMNAMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5396489 | 0.76 | KMT2A (0.58) | LMNAMAPTMEN1KMT2ARAB9A | |
| SCHEMBL6828203 | 0.75 | MAPT (0.60) | LMNAMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6825618 | 0.74 | MAPT (0.60) | TP53LMNAMAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138269-A1 | Substituted pyrroles as kinase inhibitors | SUGEN, INC. | 2004-07-15 | — | — | US | claimed |
| US-20040138269-A1 | Substituted pyrroles as kinase inhibitors | SUGEN, INC. | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138269-A1 | Substituted pyrroles as kinase inhibitors | PHKG1, PHKG2, MAP3K20 | EPHX2 2336/4885NR1H4 3711/4885TP53 1698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.