Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.46 |
| ▸ | XIAP | P98170 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6828860 | 0.85 | ALDH1A1 (0.47) | HPGDSMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL6830646 | 0.83 | ADORA2A (0.53) | HPGDALDH1A1KDM4ELMNAXIAP | |
| Hydrochloric Acid SCHEMBL6829009 | 0.83 | HPGD (0.43) | HPGDSMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL6828972 | 0.82 | TRPV4 (0.47) | HPGDSMN1; SMN2KDM4EMAPTKMT2A | |
| SCHEMBL6825783 | 0.81 | ADORA1 (0.56) | HPGDALDH1A1XIAPMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL6828816 | 0.81 | ALDH1A1 (0.47) | HPGDSMN1; SMN2ALDH1A1KDM4EPTGS2 | |
| SCHEMBL6828357 | 0.81 | ADORA2A (0.51) | XIAPMAPTKMT2AADORA2AADORA1 | |
| SCHEMBL6830910 | 0.80 | ALDH1A1 (0.46) | HPGDALDH1A1KDM4ELMNAXIAP | |
| SCHEMBL6828670 | 0.80 | XIAP (0.44) | SMN1; SMN2ALDH1A1LMNAXIAPMAPT | |
| SCHEMBL6830337 | 0.80 | ADORA2A (0.50) | SMN1; SMN2ALDH1A1KDM4ELMNAXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1441732-A2 | THIAZOLE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-04 | — | — | EP | disclosed |
| WO-2003039451-A2 | THIAZOLE PYRIDAZINONES AS ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-15 | — | — | WO | disclosed |