Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6925014 | 0.79 | TAAR1 (0.44) | ALDH1A1TSHRGAARAB9ATP53 | |
| SCHEMBL6829068 | 0.78 | RAB9A (0.49) | IKBKBALDH1A1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL2801059 | 0.74 | ALDH1A1 (0.48) | ALDH1A1GAARAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL13498020 | 0.70 | RAB9A (0.62) | ALDH1A1TSHRGAARAB9AKMT2A | |
| SCHEMBL6828231 | 0.69 | NMT1 (0.40) | ALDH1A1KDM4ELMNAHDAC3HDAC1 | |
| SCHEMBL5923376 | 0.68 | EPHX2 (0.49) | ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL5923052 | 0.67 | VCP (0.46) | ALDH1A1GAARAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL5922992 | 0.67 | RAB9A (0.56) | ALDH1A1TSHRGAARAB9AKMT2A | |
| SCHEMBL5923306 | 0.66 | ALDH1A1 (0.48) | ALDH1A1TSHRGAARAB9ATP53 | |
| SCHEMBL10853491 | 0.66 | MAPT (0.44) | ALDH1A1GAARAB9AKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037166-A2 | THERAPEUTIC GUANIDINES | ISIS PHARMACEUTICALS, INC. (US) | 2004-05-06 | — | — | WO | disclosed |