Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CCR4 | P51679 | 1/20 | 0.47 |
| ▸ | EDNRB | P24530 | 2/20 | 0.47 |
| ▸ | EDNRA | P25101 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CCR2 | P41597 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | FLT4 | P35916 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6832021 | 0.80 | POLB (0.62) | ALDH1A1MAPK1SMN1; SMN2CCR2TP53 | |
| SCHEMBL6831110 | 0.80 | VCAM1 (0.70) | ALDH1A1LMNA | |
| SCHEMBL6828427 | 0.79 | CA1 (0.61) | ALDH1A1MAPK1KMT2AFLT1FLT4 | |
| SCHEMBL644292 | 0.79 | VCAM1 (0.64) | EDNRBEDNRASMN1; SMN2KMT2ACCR2 | |
| SCHEMBL6553313 | 0.76 | PGR (0.59) | PGRALDH1A1CCR4EDNRBEDNRA | |
| SCHEMBL13290739 | 0.75 | APEX1 (0.58) | PGRALDH1A1CCR4EDNRBEDNRA | |
| SCHEMBL3062734 | 0.75 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2KMT2APKMMAPT | |
| SCHEMBL416745 | 0.75 | FLT1 (0.53) | PGRALDH1A1EDNRBEDNRAKMT2A | |
| SCHEMBL2371778 | 0.75 | FLT1 (0.49) | PGRALDH1A1EDNRBEDNRAKMT2A | |
| SCHEMBL13485852 | 0.75 | CA1 (0.64) | PGRALDH1A1FLT1FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108610304-B | Synthetic method of diaryl sultam compound | 陕西师范大学 | 2021-10-15 | — | — | CN | disclosed |
| US-20040023938-A1 | Sulfonamide derivatives | TABUCHI TAKANORI (JP) | 2004-02-05 | — | — | US | disclosed |
| US-6586617-B1 | Nontoxic microbiocides such as 4'-chloro-N-ethyl-2'-nitro-p-toluenesulfonanilide, for agricultural or horticultural, prepared by alkylation or nitration | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2003-07-01 | — | — | US | disclosed |
| EP-1174028-A1 | SULFONAMIDE DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2002-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023938-A1 | Sulfonamide derivatives | FPR1, MRM1, SULT1E1 | PGR 3980/4885ALDH1A1 453/4885CCR4 640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.