Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 8/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | FBP1 | P09467 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CCR4 | P51679 | 1/20 | 0.48 |
| ▸ | EDNRB | P24530 | 1/20 | 0.48 |
| ▸ | EDNRA | P25101 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5188198 | 0.80 | KMT2A (0.61) | MAPTLMNAFBP1ALDH1A1EDNRA | |
| SCHEMBL18770168 | 0.80 | SMN1; SMN2 (0.43) | PGRMAPTLMNAALDH1A1 | |
| SCHEMBL2371349 | 0.79 | LMNA (0.61) | PGRPKMMAPTLMNATDP1 | |
| SCHEMBL6927818 | 0.79 | PGR (0.65) | PGRPKMMAPTLMNATDP1 | |
| SCHEMBL12325142 | 0.79 | F2 (0.58) | PKMLMNATDP1ALDH1A1CYP3A4 | |
| SCHEMBL3566598 | 0.79 | PGR (0.50) | PGREDNRBEDNRA | |
| SCHEMBL6828427 | 0.77 | CA1 (0.61) | TDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL10722426 | 0.77 | ALDH1A1 (0.48) | LMNAALDH1A1TSHRCYP2C19 | |
| SCHEMBL366135 | 0.77 | CA2 (0.52) | PGRPKMLMNAALDH1A1 | |
| SCHEMBL6828477 | 0.76 | PGR (0.48) | PGRPKMMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108610304-B | Synthetic method of diaryl sultam compound | 陕西师范大学 | 2021-10-15 | — | — | CN | disclosed |
| EP-1174028-B1 | SULFONAMIDE DERIVATIVES | SUMITOMO CHEM TAKEDA AGRO CO (JP) | 2004-12-22 | — | — | EP | disclosed |
| US-20040023938-A1 | Sulfonamide derivatives | TABUCHI TAKANORI (JP) | 2004-02-05 | — | — | US | disclosed |
| US-6586617-B1 | Nontoxic microbiocides such as 4'-chloro-N-ethyl-2'-nitro-p-toluenesulfonanilide, for agricultural or horticultural, prepared by alkylation or nitration | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2003-07-01 | — | — | US | disclosed |
| EP-1174028-A1 | SULFONAMIDE DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2002-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023938-A1 | Sulfonamide derivatives | FPR1, MRM1, SULT1E1 | PGR 3980/4885PKM 4201/4885MAPT 4869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.