Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.35 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829215 | 0.83 | TERT (0.58) | TERTALDH1A1POLBL3MBTL1PTPN11 | |
| SCHEMBL6831024 | 0.82 | TERT (0.60) | TERTALDH1A1SMN1; SMN2PTPN11KDM4E | |
| SCHEMBL6830047 | 0.82 | MAPT (0.41) | TERTALDH1A1POLBHPGDSMN1; SMN2 | |
| SCHEMBL6828867 | 0.77 | ALDH1A1 (0.38) | TERTALDH1A1POLBHPGDSMN1; SMN2 | |
| SCHEMBL6826233 | 0.75 | TERT (0.54) | TERTALDH1A1POLBHPGDSMN1; SMN2 | |
| SCHEMBL6829200 | 0.75 | TERT (0.54) | TERTALDH1A1POLBL3MBTL1KDM4E | |
| SCHEMBL6829436 | 0.75 | TERT (0.52) | TERTALDH1A1POLBL3MBTL1KDM4E | |
| SCHEMBL28939851 | 0.75 | PTPN11 (0.44) | TERTALDH1A1POLBHPGDSMN1; SMN2 | |
| SCHEMBL6831027 | 0.74 | LMNA (0.51) | ALDH1A1POLBHPGDSMN1; SMN2TP53 | |
| SCHEMBL6831134 | 0.74 | RAB9A (0.40) | TERTALDH1A1POLBHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |